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THE PURSER WELLNESS REFERENCE

Your genes. More context.

Understand the names on a report, make useful connections, and keep learning at your own pace.

104 entries

Gene & pathway reference

ACE

ACE is the gene symbol used for Angiotensin-Converting Enzyme. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

ACTN3

ACTN3 is the gene symbol used for Alpha-Actinin-3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

ADIPOQ

ADIPOQ is the gene symbol used for Adiponectin, C1Q And Collagen Domain Containing. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

ADRB2

ADRB2 is the gene symbol used for Beta-2 Adrenergic Receptor. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

AHCY

AHCY is the gene symbol used for Adenosylhomocysteinase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

AOC1

Encodes diamine oxidase, an enzyme involved in breaking down histamine and other amines. DAO is used here as an enzyme nickname; it is also the official symbol of a different gene.

Gene & pathway reference

APOE

Encodes a protein involved in transporting fats. Some variants affect risk estimates, but they do not determine whether an individual will develop a disease.

Gene & pathway reference

ATG16L1

ATG16L1 is the gene symbol used for Autophagy-Related 16-Like 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

BCO1

BCO1 is the gene symbol used for Beta-Carotene Oxygenase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

BHMT

BHMT is the gene symbol used for Betaine-Homocysteine S-Methyltransferase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

BRCA1

Helps repair DNA. A clinically classified pathogenic variant has different implications from a common marker or a variant of uncertain significance.

Gene & pathway reference

BRCA2

Helps repair DNA. A clinically classified pathogenic variant has different implications from a common marker or a variant of uncertain significance.

Gene & pathway reference

C3

C3 is the gene symbol used for Complement C3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CBS

CBS is the gene symbol used for Cystathionine Beta-Synthase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CCR3

CCR3 is the gene symbol used for C-C Motif Chemokine Receptor 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CD14

CD14 is the gene symbol used for Cluster of Differentiation 14. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CHDH

CHDH is the gene symbol used for Choline Dehydrogenase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CLOCK

CLOCK is the gene symbol used for Circadian Locomotor Output Cycles Kaput. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

COL5A1

COL5A1 is the gene symbol used for Collagen Type V Alpha 1 Chain. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

COMT

Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance.

Gene & pathway reference

CTH

CTH is the gene symbol used for Cystathionine Gamma-Lyase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CUBN

Encodes cubilin, part of a receptor system involved in uptake of the intrinsic-factor–B12 complex.

Gene & pathway reference

CYP19A1

CYP19A1 is the gene symbol used for Cytochrome P450 Family 19 Subfamily A Member 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CYP1A2

CYP1A2 is the gene symbol used for Cytochrome P450 Family 1 Subfamily A Member 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CYP1B1

CYP1B1 is the gene symbol used for Cytochrome P450 Family 1 Subfamily B Member 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CYP27B1

CYP27B1 is the gene symbol used for Cytochrome P450 Family 27 Subfamily B Member 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

CYP2D6

CYP2D6 is the gene symbol used for Cytochrome P450 Family 2 Subfamily D Member 6. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

DAOA

DAOA is the gene symbol used for D-Amino Acid Oxidase Activator. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

DHFR

DHFR is the gene symbol used for Dihydrofolate Reductase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

DIO1

DIO1 is the gene symbol used for Deiodinase, Iodothyronine Type I. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

ESR1

ESR1 is the gene symbol used for Estrogen Receptor 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

ESR2

ESR2 is the gene symbol used for Estrogen Receptor 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

FADS1

Encodes an enzyme involved in fatty-acid metabolism.

Gene & pathway reference

FADS2

Encodes an enzyme involved in fatty-acid metabolism.

Gene & pathway reference

FOLH1

FOLH1 is the gene symbol used for Folate Hydrolase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

FOLR1

FOLR1 is the gene symbol used for Folate Receptor 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

FOLR2

FOLR2 is the gene symbol used for Folate Receptor 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

FOLR3

FOLR3 is the gene symbol used for Folate Receptor 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

FTO

FTO is the gene symbol used for Fat Mass and Obesity-Associated Gene. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

FUT2

FUT2 is the gene symbol used for Fucosyltransferase 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

G6PC2

G6PC2 is the gene symbol used for Glucose-6-Phosphatase Catalytic Subunit 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GABPA

Encodes a transcription-factor subunit. The uploaded reference used the label GABP1; no specific variant was established there.

Gene & pathway reference

GAD1

GAD1 is the gene symbol used for Glutamate Decarboxylase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GAD2

GAD2 is the gene symbol used for Glutamate Decarboxylase 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GCLC

GCLC is the gene symbol used for Glutamate-Cysteine Ligase Catalytic Subunit. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GCLM

GCLM is the gene symbol used for Glutamate-Cysteine Ligase Modifier Subunit. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GDF5

GDF5 is the gene symbol used for Growth Differentiation Factor 5. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GGH

GGH is the gene symbol used for Gamma-Glutamyl Hydrolase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GPX1

GPX1 is the gene symbol used for Glutathione Peroxidase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GPX3

GPX3 is the gene symbol used for Glutathione Peroxidase 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GPX4

GPX4 is the gene symbol used for Glutathione Peroxidase 4. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GSR

GSR is the gene symbol used for Glutathione Reductase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GSTM1

GSTM1 is the gene symbol used for Glutathione S-Transferase Mu 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GSTO1

GSTO1 is the gene symbol used for Glutathione S-Transferase Omega 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GSTP1

GSTP1 is the gene symbol used for Glutathione S-Transferase Pi 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

GSTT1

GSTT1 is the gene symbol used for Glutathione S-Transferase Theta 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

HDC

HDC is the gene symbol used for Histidine Decarboxylase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

HFE

Makes a protein involved in regulating iron absorption. Certain combinations of HFE variants can increase the likelihood of iron overload, but a variant alone does not establish that iron is high.

Gene & pathway reference

HLA-DQA1

HLA-DQA1 is the gene symbol used for Human Leukocyte Antigen DQA1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

HLA-DQA2

HLA-DQA2 is the gene symbol used for Human Leukocyte Antigen DQA2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

HLA-DR region

Refers to part of the HLA immune-recognition region, rather than one gene. HLA typing requires more detail than a broad region label.

Gene & pathway reference

HRH1

HRH1 is the gene symbol used for Histamine Receptor H1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

HRH2

HRH2 is the gene symbol used for Histamine Receptor H2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

IL21

IL21 is the gene symbol used for Interleukin 21. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

IL23R

IL23R is the gene symbol used for Interleukin 23 Receptor. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

IL6

IL6 is the gene symbol used for Interleukin 6. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

ITGB2

ITGB2 is the gene symbol used for Integrin Subunit Beta 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

KCTD10

KCTD10 is the gene symbol used for Potassium Channel Tetramerization Domain Containing 10. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

KIT

KIT is the gene symbol used for Kit Proto-Oncogene. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

MAOA

MAOA is the gene symbol used for Monoamine Oxidase A. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

MAOB

MAOB is the gene symbol used for Monoamine Oxidase B. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

MMP3

MMP3 is the gene symbol used for Matrix Metallopeptidase 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

MTHFD1

MTHFD1 is the gene symbol used for Methylenetetrahydrofolate Dehydrogenase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

MTHFD1L

MTHFD1L is the gene symbol used for Methylenetetrahydrofolate Dehydrogenase 1-Like. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

MTHFR

Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.

Gene & pathway reference

MTR

Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.

Gene & pathway reference

MTRR

Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.

Gene & pathway reference

NAT2

NAT2 is the gene symbol used for N-Acetyltransferase 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

NOS3

NOS3 is the gene symbol used for Nitric Oxide Synthase 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

NQO1

NQO1 is the gene symbol used for NAD(P)H Quinone Oxidoreductase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

NR3C1

NR3C1 is the gene symbol used for Nuclear Receptor Subfamily 3 Group C Member 1 / Glucocorticoid Receptor. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

NR3C2

NR3C2 is the gene symbol used for Mineralocorticoid Receptor / Nuclear Receptor Subfamily 3 Group C Member 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

NTRK2

NTRK2 is the gene symbol used for Neurotrophic Receptor Tyrosine Kinase 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

PEMT

Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency.

Gene & pathway reference

PLD3

PLD3 is the gene symbol used for Phospholipase D Family Member 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

PON1

PON1 is the gene symbol used for Paraoxonase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

PPARD

PPARD is the gene symbol used for Peroxisome Proliferator-Activated Receptor Delta. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

PSEN1

PSEN1 is the gene symbol used for Presenilin 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

PSEN2

PSEN2 is the gene symbol used for Presenilin 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

PTGS2

PTGS2 is the gene symbol used for Cyclooxygenase 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SERPINE1

Encodes plasminogen activator inhibitor-1 (PAI-1), involved in regulation of clot breakdown. A marker alone is not a reason to start aspirin or anticoagulants.

Gene & pathway reference

SHBG

SHBG is the gene symbol used for Sex Hormone-Binding Globulin. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SHMT1

SHMT1 is the gene symbol used for Serine Hydroxymethyltransferase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SLC19A1

Encodes the reduced folate carrier, a protein involved in transporting folates into cells.

Gene & pathway reference

SOD1

SOD1 is the gene symbol used for Superoxide Dismutase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SOD2

SOD2 is the gene symbol used for Superoxide Dismutase 2. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SOD3

SOD3 is the gene symbol used for Superoxide Dismutase 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SRD5A1

SRD5A1 is the gene symbol used for Steroid 5α-Reductase Type 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

SULT1A1

SULT1A1 is the gene symbol used for Sulfotransferase 1A1. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

TCN2

TCN2 is the gene symbol used for Transcobalamin II. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

TNF

TNF is the gene symbol used for Tumor Necrosis Factor. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

TPSAB1

TPSAB1 is the gene symbol used for Alpha Tryptase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Gene & pathway reference

VDR

Encodes the vitamin D receptor, which helps cells respond to the active form of vitamin D.

Gene & pathway reference

VKORC1

VKORC1 is the gene symbol used for Vitamin K Epoxide Reductase Complex Subunit 1. This page connects its terminology with the topics in the Purser Wellness teaching library.

These pages adapt the Purser educational materials into plain language. They are educational summaries, not individualized assessments or a claim of independent medical review.