Genes & pathways

Gene & pathway reference · FROM DR. PURSER’S TEACHING

TGFB1

TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

Repair signals can also promote scarring

Repair signals can also promote scarring

TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

How Dr. Purser connects the pieces

Dr. Purser discusses TGF-β in fibrosis and scarring, including selected homocysteine-related contexts. This is a reason to identify the organ and clinical process involved rather than treating every elevated inflammatory marker as the same problem. A common variant does not establish fibrosis.

Where the VARS Triad and MTHFR Daily fit

In Dr. Purser’s treatment framework, the VARS Triad—VARS Glutathione, VARS SOD and VARS Catalase—together with MTHFR Daily is a central consideration when homocysteine or cytokine issues are involved. He emphasizes VARS Glutathione as a foundational functional-support component across his genetic SNP teaching. The individual gene lesson explains how its pathway connects to that broader approach.

This describes the Purser treatment model, not proof that a product corrects a variant or treats every associated condition. Product choice, formulation, sequence and amount depend on the individual assessment, existing medicines, current findings and tolerance.

A question to bring to your visit

Is there objective evidence of scarring in a specific organ, and what is the underlying cause?

Variant lookup

These teaching identifiers include regional research markers. Match them to your original laboratory report; listing alone does not establish clinical significance or a treatment need.

Names you may see

TGF-beta · TGF-β · Transforming growth factor beta 1