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Encodes the reduced folate carrier, a protein involved in transporting folates into cells.
Connections in the Purser reference
The Purser reference connects folate transport with methylation and nutrient interpretation. A transport-related genetic finding does not establish folate deficiency.
Understanding a result
A gene name is not a test result. Interpretation needs the exact variant, genotype, test method, clinical classification, symptoms and family history. Research associations and common SNPs should not be treated as proven disease-causing findings.
Folate, B12 and next steps
Food intake, medicines and clinical findings matter alongside genetics. A variant alone does not select folic acid, folinic acid or methylfolate for an individual.
Questions for your visit
Is this a common marker, a pathogenic variant, or an uncertain finding? Does it change my care? Would confirmation or genetic counseling be useful?
Names you may see
RFC1 · reduced folate carrier · folate transport
Sources & perspective
This is an editorial adaptation of the Purser Wellness genetics teaching app and genetic rules reference (v2.8). Purser teaching connections are labeled separately from clinical interpretation. Private cases and individual treatment protocols are not reproduced.
Use the public resources below for additional context.
MedlinePlus: understanding genetic resultsNCBI ClinVar: clinical classifications