Genes & pathways

Gene & pathway reference · FROM DR. PURSER’S TEACHING

IL18R1

IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

The binding side of the IL-18 receptor

The binding side of the IL-18 receptor

IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.

How Dr. Purser connects the pieces

Dr. Purser connects this receptor pathway with celiac and inflammatory bowel disease contexts. A gene for receiving a signal is distinct from the gene that produces it. Symptoms and standard diagnostic testing should determine whether a gut inflammatory disorder is present.

Where the VARS Triad and MTHFR Daily fit

In Dr. Purser’s treatment framework, the VARS Triad—VARS Glutathione, VARS SOD and VARS Catalase—together with MTHFR Daily is a central consideration when homocysteine or cytokine issues are involved. He emphasizes VARS Glutathione as a foundational functional-support component across his genetic SNP teaching. The individual gene lesson explains how its pathway connects to that broader approach.

This describes the Purser treatment model, not proof that a product corrects a variant or treats every associated condition. Product choice, formulation, sequence and amount depend on the individual assessment, existing medicines, current findings and tolerance.

A question to bring to your visit

Are we investigating a confirmed gut inflammatory condition or only a susceptibility marker?

Variant lookup

These teaching identifiers include regional research markers. Match them to your original laboratory report; listing alone does not establish clinical significance or a treatment need.