Genes & pathways

Gene & pathway reference · FROM DR. PURSER’S TEACHING

IL23A

IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.

Updated Sep 23, 2026 · Educational reference

THE TEACHING CONNECTION

The p19 component of IL-23

The p19 component of IL-23

IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.

How Dr. Purser connects the pieces

Dr. Purser discusses IL23A in colitis and psoriasis-related teaching. Linking IL23A to IL23R and IL17A makes the sequence easier to follow: produce the cytokine, receive its signal and maintain a downstream inflammatory response. Genetic associations do not identify the correct immune treatment by themselves.

Where the VARS Triad and MTHFR Daily fit

In Dr. Purser’s treatment framework, the VARS Triad—VARS Glutathione, VARS SOD and VARS Catalase—together with MTHFR Daily is a central consideration when homocysteine or cytokine issues are involved. He emphasizes VARS Glutathione as a foundational functional-support component across his genetic SNP teaching. The individual gene lesson explains how its pathway connects to that broader approach.

This describes the Purser treatment model, not proof that a product corrects a variant or treats every associated condition. Product choice, formulation, sequence and amount depend on the individual assessment, existing medicines, current findings and tolerance.

A question to bring to your visit

Which established clinical findings make the IL-23/IL-17 connection relevant?

Variant lookup

These teaching identifiers include regional research markers. Match them to your original laboratory report; listing alone does not establish clinical significance or a treatment need.

Names you may see

IL-23A · Interleukin 23A