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Are your B vitamins making you feel worse instead of better? Methylated B vitamins can be incredibly helpful for energy, homocysteine metabolism, neurological health, and many essential processes. But the right nutrient can become the wron

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Can’t absorb iron no matter what you try? 😣 It might not be the iron — it’s your B vitamins. Fix the deficiency → fix the absorption.

If you feel exhausted, irritable, or worse after taking methylated B vitamins, you may be overmethylating. Too many methyl groups can act like a “toxic overload,” leaving you sleepy or edgy. The fix is simple: stop high-dose methyl B’s and

ATP and MTHFR are closely correlated. If you cannot process folate and other B vitamins, you’re going to be tired due to inefficient ATP production. This causes chronic fatigue and other symptoms. So make sure to take your MTHFR Renew and M

If you are low or think you're low in Iron, you HAVE to try Vitamin B12 and Vitamin C to boost your levels. Seeking Health has a great Methyl Free B vitamin complex, and our VARS Vitamin C from PhysicianDesigned.com is your best option for FUNCTIONAL vitamin C. Boost your levels and always remember you can get a CMA Intracellular Test if you want to see your other levels. Reach to my office with any questions. 801-796-7667 Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore

What if the key to feeling better isn't another health trend—but understanding the nutrients your body depends on every day? Vitamin C. B vitamins. Iron. These essential nutrients influence everything from energy production and immune fun

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore iron levels within a few months. Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

😴 Feel like you took 3 Dramamine but all you had was a vitamin? You might be overmethylating—especially if you're taking too much MTHFR support like methylated B vitamins. If you’re drowsy, foggy, or exhausted, it’s time to back off, not pu

😴 Feel like you took 3 Dramamine but all you had was a vitamin? You might be overmethylating—especially if you're taking too much MTHFR support like methylated B vitamins. If you’re drowsy, foggy, or exhausted, it’s time to back off, not push through. Try dropping to 1 capsule of MTHFR Daily and adjust slowly. Your body will thank you. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd