Energy & metabolism

A subscriber episode exploring questions about MTHFR, nutrient status, and daily energy. Read the public introduction and continue on Substack.

Dan and Jackson discuss methylated B vitamins, the term overmethylation, and questions to ask when your response to a supplement changes.

Dan Purser MD and Jackson Larkin discuss the connections they consider between sugar cravings, cellular energy, and methylation.

PURSER WELLNESSUnderstanding Your CMA with Redox Results: What Those Two Pages Actually MeanA conversation with Dr. Purser

If you’ve had our Cellular Micronutrient Assay (CMA) with Redox testing, chances are you’ve looked at those two pages of results and thought, “Okay... now what does all this actually mean?” You’re not alone. This is one of the questions I hear most often from patients. Let me walk you through exactly what each page shows, how the test works, and why these results are so powerful for creating a truly personalized plan to help you feel your best.

From Brain Fog to Burnout: The Hidden Deficiencies Your Bloodwork Misses. By Dan Purser MD

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors MissFrom the reading room

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation. This is not fringe theory. It is the clinical reality I have

A episode from Purser Wellness on Substack, covering energy and metabolism, testing and nutrients.

PURSER WELLNESSCoQ10 and Thyroid MedicationA conversation with Dr. Purser

CoQ10 is an important nutrient that improves hypothyroidism and metabolism naturally. Explore how CoQ10 can help you with your energy levels and feel younger!

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model, which explains why homo