IL22 encodes a cytokine that acts on tissues such as epithelial barriers. It can support barrier defense and repair, while its effects depend on the tissue and inflammatory setting.
Also called:
Barrier defense, repair and excess tissue gr…
IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.
Also called:
The p19 component of IL-23
IL23A encodes the p19 subunit of interleuki…
IL2RA encodes the alpha chain of the interleukin-2 receptor, also called CD25. It is involved in immune activation and regulatory T-cell biology; a soluble receptor measurement is distinct from a DNA result.
Also called:
CD25 and immune-ce…
IL33 encodes interleukin-33, a signal that can act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells.
Also called:
An alarmin in allergic s…
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
IL5 encodes interleukin-5, a cytokine important to eosinophil growth, survival and activation. Eosinophils are involved in selected allergic and other inflammatory conditions.
Also called:
An eosinophil-focused cytokine
IL5 encodes interle…
IL6R encodes the interleukin-6 receptor. Membrane-bound and soluble receptor pathways help explain why IL-6 biology involves more than the amount of cytokine in a single blood sample.
Also called:
Receiving and relaying the IL-6 signal
IL6…
MTHFS encodes an enzyme that converts 5-formyltetrahydrofolate into 5,10-methenyltetrahydrofolate. This places it in folate interconversion; it is not another name for MTHFR or a direct maker of methylfolate.
Also called:
Folinic acid has …
TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.
Also called:
Repai…
TNFRSF10A encodes death receptor 4, or DR4, a receptor that can receive the TRAIL signal and participate in regulated cell-death pathways. TRAIL itself is encoded by TNFSF10.
Also called:
DR4 receives the TRAIL signal
TNFRSF10A encodes dea…
ACE is the gene symbol used for Angiotensin-Converting Enzyme. This page connects its terminology with the topics in the Purser Wellness teaching library.
Also called: Angiotensin-Converting Enzyme
Start here
ACE is the gene symbol used for…
ACTN3 is the gene symbol used for Alpha-Actinin-3. This page connects its terminology with the topics in the Purser Wellness teaching library.
Also called: Alpha-Actinin-3
Start here
ACTN3 is the gene symbol used for Alpha-Actinin-3. This p…
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