Let’s explore “Homocysteine, total — lab reference”

…es Dr. Purser’s notes connect MTHFS with folate support and homocysteine. The useful lesson is that the form of folate matters and that several enzymes connect those forms. Discuss the actual product and response alongside B12 and homocyste…

…iscusses TGF-β in fibrosis and scarring, including selected homocysteine-related contexts. This is a reason to identify the organ and clinical process involved rather than treating every elevated inflammatory marker as the same problem. A c…

PURSER WELLNESSOVER-METHYLATION - Are Your B Vitamins Hurting You?A conversation with Dr. Purser

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSGlutathione and Your Ability To Detox?A conversation with Dr. Purser

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine storms. That’s why VARS Glutathione is such a breakthrough: it’s reduced, functional, and proven to lower harmful cytokines like IL-8 and MCP-1, giving your body the detox power it needs. After 15 years of research and real patient results, it’s the only oral glutathione that actually works where it matters—inside your cells.

Everyone talks about MTHFR. But what if that is only one piece of the puzzle? MTHFR helps process folate, while MTR helps recycle homocysteine back into methionine with the help of vitamin B12. Two genes. Different roles. One interco

The Purser genetics reference places CHDH in choline metabolism, while the combined SOP asks clinicians to consider CHDH alongside PEMT and FADS findings.

The older Purser genetics reference uses the heading “DAOA (AOC1)” in its gut section.

Good questions deserve a deeper conversation. Purser Wellness Explore is a new space to follow yours - videos, articles, and guided journeys with me. Start with MTHFR, cytokines, homocysteine, gut health… or whatever thread you’re holding

Encodes a transcription-factor subunit. The uploaded reference used the label GABP1; no specific variant was established there.

This report overview covers folate, vitamin B9, one-carbon metabolism, anemia, homocysteine, SLC19A1, and the report’s comparisons of folate forms and transport pathways.

This report overview covers rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and the report’s discussion of double homozygosity.

Are your B vitamins making you feel worse instead of better? Methylated B vitamins can be incredibly helpful for energy, homocysteine metabolism, neurological health, and many essential processes. But the right nutrient can become the wron