THE PURSER WELLNESS LIBRARY

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A COURSE FOR YOUR CURIOSITYYour MTHFR starting point

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SubstackMar 2, 2026

Can Glutathione Reverse Kidney Disease, Lower Blood Pressure, and Calm Cytokine Storms? What High Homocysteine May Be Doing to Your Arteries, Kidneys, and Fertility

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The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step

YouTubeJan 6, 2026

How To Know If You Have High Homocysteine?

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High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

YouTubeJan 6, 2026

What Happens If You Have A Gene SNP?

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Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

YouTubeJan 6, 2026

Gene Types Explained

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Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.

YouTubeJan 6, 2026

Remove inflammation by combatting High Homocysteine

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High homocysteine levels can lead to inflammation, joint and muscle pain, and even shifting pain throughout the body. It’s also linked to birth defects and chronic kidney failure, and can raise blood pressure. Six genetic SNPs (like MTR, MTRR, and CBS) and MTHFR mutations (like C677T) can prevent homocysteine from converting into glutathione, which is essential for keeping inflammation in check. Plus, 12 vitamin deficiencies may temporarily raise homocysteine levels, so addressing these deficiencies is key.

YouTubeJan 6, 2026

Doctor Reacts to Gary Brecka om Joe Rogan - MTHFR and MORE!

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Dan Purser MD, renown for his work with MTHFR, chronic fatigue, anxiety, depression, fertility, hormone health, fibromyalgia, and SO MUCH MORE takes on the recent podcast interview of Gary Brecka from 10 Times Health System and Joe Rogan. Mr. Brecka is correct on so many points, but there is still SO MUCH MORE to dive into. The 5 genes he looks at are critical, but there are several to dozens more that need to be addressed. Once you look at genes, you must check out Intracellular Micronutrient Levels. This is THE ONLY way to get the full picture.

YouTubeJan 6, 2026

How to Lose Weight with MTHFR!

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It is never easy to lose weight and it is much harder for people with MTHFR. If you have MTHFR, and are struggling with your weight, here is a quick rundown of one reason it may be along with a couple of tips to help you on your weight loss journey! Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

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