Substack·Published: May 1, 2026

MTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss

About this Substack post

A Guide by the World’s Leading Homocysteine Expert

ONE MORE CONNECTION MADE

Keep your curiosity going.

FOLLOW THE THREAD

Make sense of the vocabulary. Explore MTHFR, genetic variants, and the conversations around methylation.

A note on the archive

This listing summarizes the public topic of the original post. Visit Substack for the author’s discussion and any required subscriber access.

Subscriber

Substack2026

Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.

Subscriber

Substack2026

Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.

Subscriber

Substack2026

Dr. Purser’s subscriber report on IL-10 dysregulation, immune signaling, and his discussion of the VARS Antioxidant Triad.

Subscriber

Substack2026

Dr. Purser’s subscriber report on IL-17, homozygosity, and the skin, joint, and digestive topics raised in the public introduction.