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This is a clip from https://danpursermd.substack.com/p/mthfr-and-the-never-ending-sugar?utm_source=youtube_shorts See the full video: https://www.youtube.com/watch?v=0BGJ_m5Cbrc #shorts #substack

That afternoon sugar craving may be telling you more than you think. Here’s how methylation, glucose, cellular energy and your genetics may fit into the bigger picture. https://danpursermd.substack.com/p/mthfr-and-the-never-ending-sugar?utm_source=youtube

Certain genetic variants can affect MTHFR enzyme activity, which is why understanding your individual biology can change the conversation around nutrition. That is where MTHFR Daily comes in. Designed with methylation support in mind, MTH

You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

🚨 Why do you keep craving sugar and crashing even when you’re trying to eat healthy? If you have an MTHFR variant, it’s likely NOT just willpower — it’s a methylation & energy production issue at the cellular level. In our latest video, we

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

What if brain fog isn't a normal part of getting older? What if it's your body's way of telling you something is wrong? Too many people have accepted forgetfulness, poor focus, mental fatigue, and difficulty concentrating as part of every

Struggling to feel better, even with a methylation support supplement? Here’s why it might not be working—and what you can do to finally see results.

Explore with Dr. Purser how methylation errors may be causing your fatigue. Be sure to check out the End Fibromyalgia with Natural Options Facebook page for more help and tips at facebook.com/NaturalOptionsWithLois/

Not all genetic tests are created equal. Many only scratch the surface, while the best panels look at hundreds of SNPs that impact methylation, detox, hormones, and nutrient absorption. For real results, you need a test that’s private, comprehensive, and clinically useful—like the ones we recommend in practice that help guide targeted treatment plans.

This week Dr. Purser shares his findings and treatment protocols for Interstitial Cystitis. He classifies this disease as the worst version of fibromyalgia, but covers best ways to treat it. Try a low copper diet, understand your underlying methylation genetics, and use beneficial supplements. Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!