WHAT DOES A defective MTHFR gene structure do to you?

WHAT DOES A defective MTHFR gene structure do to you?

1. It causes a reduction in the production of the critical MTHFR enzyme, causing methylation to occur at only 40% of a healthy body’s capacity, or even as much as 70% of its capacity (still bad though). It can mean you could have been diagnosed with heavy metal toxicity – you won’t break down toxins or heavy metals fast enough – i.e. you could find yourself with high iron, or high copper, or high lead, or high mercury….etc. High copper can also cause low ferritin, even though your iron levels look great.

2. The defective enzyme doesn’t break down folate vitamins properly (of which folic acid is the precursor to), which can cause high homocysteine levels (hyperhomocysteinemia), which causes vascular inflammation which in turn can increase your risk of coronary heart disease (arteriosclerotic vascular disease or venous thrombosis), and related heart and high BP conditions, as well as increasing your risk for dementia. (This vascular inflammation can explain why someone young has high blood pressure of unknown cause—in turn when treated, their BP should drop to normal).

3. Homocysteine is poorly converted to methionine, and less methionine can raise your risk of arteriosclerosis, fatty liver degenerative disease, anemia, increased inflammation, increased free radical damage… and produce less SAMe.

4. You can become toxic with high folate or high B12 levels, i.e. your body will have problems converting inactive forms of folate and B12 to the active forms. So the inactive folate or B12 will simply build up in your serum, also inhibiting the active forms. Most serum folate tests are actually measuring folic acid, which needed to be converted to methylfolate to be used metabolically.

Glutathione and a blend of methylated B vitamins and minerals can help support these issues. PhysicianDesigned.com supplements are the ONLY products designed from the ground up to support methylation errors.