Homocysteine: how the story developed
Trace the chapter’s account of homocysteine, from early biochemical discoveries and homocystinuria to the debate over cardiovascular risk.
THE PURSER WELLNESS LIBRARY
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What’s searchable?Understanding homocysteine and its pathways
An introduction to the chapter’s discussion of homocysteine metabolism, nutritional cofactors and the many influences on a blood result.
Genes in the homocysteine conversation
A reading guide to Dr. Purser’s chapter listing genetic variants discussed in relation to elevated homocysteine.
Nutrition and unexpectedly low homocysteine
Explore the chapter’s hypothesis that nutritional status can complicate interpretation of a low homocysteine result.
Homocysteine, monocytes, IL-8 and MCP-1
Follow the chapter’s proposed bridge between homocysteine and inflammatory messages released by monocytes.
Genetics and the transsulfuration pathway
This chapter connects genetic variation with the sulfur pathway that appears throughout Dr. Purser’s redox teaching.
Homocysteine, inflammation and pain
A guide to the chapter’s proposed connections between homocysteine, inflammatory signaling and pain.
Homocysteine, D-dimer and inflammatory markers
Explore how this chapter relates homocysteine to clotting and inflammatory laboratory markers.
Two studies behind the homocysteine–glutathione model
Understand why Dr. Purser places two experimental research discussions at the center of his inflammatory model.
Homocysteine and environmental exposures
This chapter places environmental exposures alongside genetics, sulfur metabolism and inflammatory markers.
Homocysteine and cardiovascular risk
A guide to the chapter’s discussion of homocysteine, vascular injury and cardiovascular or cerebrovascular outcomes.
IL-8, MCP-1 and kidney inflammation
Explore the kidney chapter’s account of immune-cell recruitment, small-vessel injury and fibrosis.
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