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… not prove a clinical benefit. Glutathione and inflammatory signals Glutathione helps your cells respond to oxidative stress. In Dr. Purser’s model, this may also connect with immune signals called IL-8 and MCP-1. This is one reason he look…

… places AOC1 in the histamine-clearance part of the gut and immune story. The enzyme it encodes, diamine oxidase, helps break down histamine and related amines. That is a different job from HDC, which helps make histamine, or HRH1 and HRH2,…

…s demonstrating prevention of every associated disease. How immune signals may connect In Dr. Purser’s model, homocysteine may relate to how cells respond to inflammation. He discusses genes, nutrients, antioxidant status, and the immune si…

…r. Purser discusses IL-22 in mucosal protection, psoriasis, ulcerative-colitis and pregnancy-related inflammatory contexts. These different roles explain why simply describing a cytokine as good or bad is incomplete. A variant cannot establ…

…. Putting the pieces together Dr. Purser discusses IL23A in colitis and psoriasis-related teaching. Linking IL23A to IL23R and IL17A makes the sequence easier to follow: produce the cytokine, receive its signal and maintain a downstream inf…

…part of the wider methylation, nutrient and redox picture. Immune signal connection High homocysteine and IL-8 / MCP-1 Immune cells · CXCL8 / IL-8 · CCL2 / MCP-1 Not a nutrient or metabolic reaction When homocysteine is high, some studies …

… also called MIP-1 beta, is a chemical signal that attracts immune cells, particularly through CCR5. It is related to CCL3, but the two signals do not have identical roles. Follow the pathway Dr. Purser connects CCL4 with T-cell and macrop…

…A1. Understand the connection A cytokine panel can include immune messengers, chemokines that guide cell movement, receptors that receive signals, and proteins with other roles. These categories answer different questions. Follow the path…

…ions. Understand the connection IL-17A is part of the Th17 immune pathway and helps organize responses at barrier tissues. It can stimulate other cells to release signals that recruit neutrophils. Follow the pathway Dr. Purser discusses r…

…r cells. Injury or stress can release it, helping alert the immune system that tissue needs attention. Follow the pathway Dr. Purser discusses the ST2 receptor, type 2 immune responses, and signals involving eosinophils and allergic inflam…

…(NAFLD) 🚨 Gallbladder disease 🚨 Pancreatitis 🚨 Crohn’s & Ulcerative Colitis 🚨 Indigestion, bloating, & nausea from poor bile flow PEMT & Gut Health: The Crohn’s & Colitis Connection 🔬 Studies show that patients with Crohn’s & UC have …

…f the population. It can cause symptoms similar to Crohn’s, ulcerative colitis, and even pancreatitis! The solution? Phosphatidylcholine and glutathione. Our VARS Glutathione delivers both, using sunflower lecithin liposomes for maximum ab…