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…edicine right now. We figured out a lot about medicine, autoimmune diseases and there's so much research on it. It's crazy that the immunologists and the doctors can't my fellow physicians can't figure these cases out. They just throw their…

…tep in. We deal with about one POI case a week uh premature ovarian insufficiency and it's those are bad. Um sometimes we can bring them all the way back to start their periods again. Then if they have the right vitamin deficiencies, someti…

… taking a Young Living supplement every single day that the primary ingredients are mushrooms because it's good for your immune system. And I never thought about I knew I wasn't eating any mushrooms, but I hadn't thought about, oh, I'm taki…

…n is a crucial biological procedure involved in DNA repair, immune function, mood balancing, and detoxification, among other processes. Mutations of the MTHFR gene can potentially affect the enzyme's activity, leading to inefficient methyl…

Explore the possible links between homocysteine, immune signaling, and pain.

…tion According to the Purser Model, homocysteine is not the primary cause of tissue damage. Instead, it acts as a marker of cytokine sensitivity . Cytokines are inflammatory signaling molecules released by immune cells. When homocysteine ri…

…ain, fatigue, and brain fog can arise from many conditions. Immune signals such as TNF-alpha and IL-6 are relevant to some inflammatory illnesses, but symptoms alone cannot identify the cause. Follow the pathway Dr. Purser explains the rel…

…Follow the pathway Dr. Purser connects endothelial changes, immune signals, TGF-beta-related fibrosis, and Raynaud’s phenomenon. Tissue scarring and inflammatory activity are related but do not mean every symptom has the same cause. Bring …

… not prove a clinical benefit. Glutathione and inflammatory signals Glutathione helps your cells respond to oxidative stress. In Dr. Purser’s model, this may also connect with immune signals called IL-8 and MCP-1. This is one reason he look…

… places AOC1 in the histamine-clearance part of the gut and immune story. The enzyme it encodes, diamine oxidase, helps break down histamine and related amines. That is a different job from HDC, which helps make histamine, or HRH1 and HRH2,…

…s demonstrating prevention of every associated disease. How immune signals may connect In Dr. Purser’s model, homocysteine may relate to how cells respond to inflammation. He discusses genes, nutrients, antioxidant status, and the immune si…

…part of the wider methylation, nutrient and redox picture. Immune signal connection High homocysteine and IL-8 / MCP-1 Immune cells · CXCL8 / IL-8 · CCL2 / MCP-1 Not a nutrient or metabolic reaction When homocysteine is high, some studies …