Let’s explore “homocysteine”

Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.

Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.

This report overview covers folate, vitamin B9, one-carbon metabolism, anemia, homocysteine, SLC19A1, and the report’s comparisons of folate forms and transport pathways.

This report overview covers rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and the report’s discussion of double homozygosity.

PURSER WELLNESSToxins Are Especially Bad For YOU!A conversation with Dr. Purser

Why do some people in the same family get destroyed by black mold… while others are completely fine? Why do two kids develop autism while their siblings are completely normal? Dr. Dan Purser explains the hidden genetic issue behind both: a homocysteine problem that disrupts the transsulfuration pathway — the pathway responsible for making ~90% of your glutathione. Without enough glutathione, your body simply cannot clear toxins. Mold, heavy metals, environmental chemicals… they stay stuck. This is why some people get chronically ill and others don’t, even when living in the exact same house. In this episode we cover: How a genetic disruption in the transsulfuration pathway causes low glutathione Why most “glutathione” products on Amazon do nothing The only two patented forms that actually work Real cases of black mold toxicity and autism improvement Why checking genetics is more important than just checking a homocysteine level This is root-cause medicine — not symptom chasing. Learn more: Website: https://danpursermd.com Two Glutathione: https://twoglutathione.com Substack: https://danpursermd.substack.com Office: (801) 796-7667 Email: info@danpursermd.com #Homocysteine #Glutathione #BlackMold #Autism #Detox #RootCauseMedicine #PurserWellness #Genetics

This report overview covers the reduced folate carrier (RFC1), rs3788200, rs1051266, intracellular folate, homocysteine, and the report’s discussion of folinic acid and methylfolate.

PURSER WELLNESSWhat is VARS? Super Antioxidant Protection?A conversation with Dr. Purser

🔬 What is VARS? Why the VARS Trio (Glutathione + SOD + Catalase) is a game-changer for inflammation, recovery & fibromyalgia. Jackson Larkin sits down with Lois Schweiger to break down Dr. Dan Purser MD’s VARS line — Validated, Absorbable, Reduced, and Stable antioxidants. Learn the science behind VARS Glutathione, VARS SOD (from deep-sea algae near volcanic vents), and the newest VARS Catalase (Nrf2 activator from seaweed). Discover: • How the VARS Triad works together in the mitochondria to fight oxidative stress and cytokines • Why Catalase dramatically improved post-workout recovery (especially leg day!) • Genetics, homocysteine, PEMT, and why many with fibro benefit from this protocol • The importance of CMA (intracellular) testing and when to retest • Real patient results, including severe inflammation cases Perfect for anyone dealing with chronic pain, inflammation, slow recovery, or looking for root-cause support. **June Anniversary Special**: $100 off Genetic + CMA testing — one order will be fully reimbursed! 👉 Learn more & shop VARS supplements: danpursermd.com #VARSGlutathione #Fibromyalgia #Antioxidants #ChronicInflammation #PurserWellness #Catalase #SOD Timestamps: 00:00 Intro & What Does VARS Mean? 01:45 The Science of the VARS Triad 12:00 Who Needs the Trio? 14:00 Catalase & Workout Recovery Stories 20:00 Genetics, Homocysteine & Testing Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSVARS TRIAD | What Does That Mean? | Live with Dan Purser MDA conversation with Dr. Purser

Discover the power of the VARS Triad (also called the REDOX Triad)—Dr. Dan Purser MD’s groundbreaking, patented antioxidant protocol featuring VARS Glutathione, VARS SOD, and VARS Catalase. In this live session, Dr. Purser breaks down what VARS stands for (Validated, Absorbable, Reduced, Stable), how this physician-designed trio supports your body’s natural redox balance, quiets inflammation and cytokines at the root-cause level, and helps overcome genetic challenges like high homocysteine, oxidative stress, and related chronic issues. Perfect for anyone exploring advanced functional medicine and targeted supplementation. Learn more at https://physiciandesigned.com/blogs/glutathione/discover-the-vars-trio-your-bodys-ultimate-antioxidant-powerhouse

PURSER WELLNESSWhere To Find Dr. Purser Online (Deplatformed)A conversation with Dr. Purser

Dr. Dan Purser here with an important update from Purser Wellness. Earlier this week we were deplatformed on a major platform right after discussing groundbreaking findings from our homocysteine research — particularly its connections to ASD, ADHD, cytokine issues, and inflammatory conditions like polymyalgia rheumatica (PMR). Despite losing access to our old page (and nearly 200,000 followers), we’re back stronger with a brand new official page! ✅ Follow our new official Facebook page here: https://www.facebook.com/purserwellness We’re keeping things focused and continuing our important work on root-cause wellness, intracellular nutrient deficiencies, genetics, glutathione/SOD balance, and more. ### Where to Stay Connected: - Substack (Daily research articles & in-depth content): https://substack.com/PurserWellness or https://danpursermd.substack.com - YouTube – Live streams and full recordings will continue here (plus TikTok, Instagram, and podcast platforms) Dr. Purser’s message is clear: We will not stop the research. “I’ll quit when I die… and maybe not even then.” If you’ve been following our work on homocysteine, MTHFR, cytokine problems, hormone optimization, and functional medicine protocols, please: - Like and follow the new Facebook page - Subscribe to Substack - Share this video with friends and patients who need this information Thank you for your incredible support during this transition. Your follows and shares help us keep delivering the cutting-edge research no one else is doing. 👉 New Facebook Page: https://www.facebook.com/purserwellness Purser Wellness Root-Cause Medicine • Genetics • Homocysteine Research danpursermd.com #DrDanPurser #PurserWellness #Homocysteine #FunctionalMedicine #RootCauseHealth #CytokineResearch #ASD #ADHD #MTHFR

PURSER WELLNESSAutism Answered - Root Cause Solved with #1 Reviewed MD in the USAA conversation with Dr. Purser

Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

How Broken Methylation, High Homocysteine, and Depleted Glutathione Are Driving the Rise Since the 1980s

And Why Your Methylation, Homocysteine, and Glutathione Pathways Are the Missing Link