Every woman with PCOS I’ve ever tested has a homocysteine problem...
That’s what Dr. Dan Purser says — and it might explain why so many women with PCOS struggle with pain, inflammation, fatigue, and even kidney or blood pressure issues.
Homocysteine isn’t just a lab number — it’s a toxic byproduct that drives inflammation through cytokines like MCP-1 and IL-8, damaging blood vessels and disrupting hormones.
Dr. Purser’s research found up to 17 genetic SNPs that can keep homocysteine high — and whether you have one or all 17, the result is the same: inflammation, oxidative stress, and worsening PCOS symptoms.
Doctors used to treat it by restricting nutrients — but that failed. The key is to address the root cause: methylation and nutrient deficiencies (B12, folate, B6, and more).
High homocysteine isn’t just a number on a test.
It’s one of the biggest, most overlooked drivers of PCOS symptoms — and it’s fixable.
