… evidence supports changing it?
Variant IDs in the teaching reference: rs6495446
Also called: 5-formyltetrahydrofolate cyclo-ligase
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may disc…
…d what is the underlying cause?
Variant IDs in the teaching reference: rs1800469, rs1800470, rs1800471
Also called: TGF-beta, TGF-β, Transforming growth factor beta 1
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocystein…
…is its cause being established?
Variant IDs in the teaching reference: rs20575
Also called: DR4, Death receptor 4
Where the VARS Triad and MTHFR Daily fit
If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily an…
…ed in controlling how other genes are used. You may see the label GABP1 in older materials; check the exact variant on your own report.
Also called: GABP1, GA Binding Protein Transcription Factor Subunit Alpha
Start here
GABPA is a gene inv…
…ition.
Support methylation when appropriate.
Prioritize protein, fiber, and healthy fats.
Move your body.
Protect your sleep.
Manage stress.
And when symptoms persist, consider looking deeper into your labs, genetics, and indivi…
…d alongside kidney function, nutrition, genetics, and other laboratory findings.
Your lab results are more than numbers on a page.
They are clues that can help you ask better questions about your health.
Learn why kidney health and homoc…
…s can be more complicated than simply looking at a standard lab panel.
A CMA is designed to provide another perspective on how your cells respond to essential nutrients, giving you and your healthcare team additional information to conside…
…lular testing
✅ Intermittent fasting + fasted cardio
✅ High-protein, real-food eating
If you’re tired of feeling tired and stuck in the sugar trap, this one’s for you.
Make sure you’re following our Purser Wellness Substack for more deep …
…HFR C677T/A1298C—includes MTR, MTRR, CBS, PEMT, etc.). Most labs stop at two SNPs. I test 22 because real patients have compound defects. Intracellular Micronutrient Testing to catch functional folate, B12, B6, and glutathione deficiencies …
… kidney or blood pressure issues.
Homocysteine isn’t just a lab number — it’s a toxic byproduct that drives inflammation through cytokines like MCP-1 and IL-8, damaging blood vessels and disrupting hormones.
Dr. Purser’s research found up t…
Thyroid health remains essential during menopause. Optimal labs should show FT3 around 4.0 and FT4 near 1.5, and testing through Direct Labs makes it easy to track. Supporting with supplements like Thyromin can help, but only if guided by a…
…The solution is supporting ceruloplasmin—the copper-binding protein—with targeted nutrients like B6, zinc, and NAC. That’s why Copper Balance was created: to move copper where it belongs and help symptoms finally improve. Visit PhysicianDes…
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