…illnesses. That organization helps readers see connections: blood pressure and glucose appear in cardiovascular, kidney and brain-health discussions, while nutrition and activity cross many chapters. The book’s age matters when reading nume…
…testicular changes, red-cell counts, acne, fluid retention, blood pressure and injection-site problems. It also makes broader comparative claims about formulations. The useful questions are which risks are relevant to your prescription, how…
…ness and stress testing. It lists lipid-lowering medicines, blood-pressure management, thyroid and hormone ideas, glutathione, fasting and other interventions. These are searchable source topics, not a list of endorsed therapies. Ask whethe…
…radiol, oral versus topical routes, timing after menopause, blood pressure, clotting history, Factor V Leiden and cancer history. These topics help organize a conversation about eligibility and individual risk.
The history shapes the hormo…
Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions.
For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered.
New research and clinical observations are changing that view.
We introduce a new framework called the Purser Model, which explains why homo
Intracellular testing, or the CMA Cellular Micronutrient Assay, measures over 100 vitamins, minerals, amino acids, and antioxidants inside your cells—not just in your blood. Unlike serum tests, which show short-term levels, intracellular testing reveals what your cells have been missing over the last 100 days. Low levels can mean weak enzymes, non-functioning proteins, and accelerated aging. By identifying deficiencies and matching them with the correct nutrient forms for your genetics, you can target fatigue, anxiety, depression, and other chronic issues at the root. Get your CMA by calling o
This report overview covers HbA1c, red blood cell turnover, hemoglobin variants, blood loss, hypoglycemia, and the factors the source discusses when interpreting a low A1C result.
This report overview covers dimethylarginine dimethylaminohydrolase 1 (DDAH1), asymmetric dimethylarginine (ADMA), nitric oxide, blood vessels, and the cardiovascular pathways discussed in the source.
MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets
If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.”
In this video, we break down exactly why this happens:
How MTHFR/methylation issues impair ATP (energy) production at the cellular level
Why your body desperately reaches for quick glucose
The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage
The downstream effects on antioxidants, DNA repair, and overall energy
How to finally break the cycle:
Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests)
Why our MTHFR Daily multivitamin was specifically formulated for this
The power of CMA intracellular testing
Intermittent fasting (12–16 hrs)
Fasted cardio (even just a brisk walk)
High-protein, real-food diet with minimal processed sugars
If you’re tired of the sugar rollercoaster and want stable energy, this is for you.
Links:
Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle
Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com
Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily
Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious!
#MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
Best match puts all-term matches before partial matches and related reading. Matching long titles across sources are grouped when access is the same. Search covers published titles, descriptions, available article text, report overviews, and the full text of the nutrient, gene and learning-essential reference pages. Books, uploaded chapters and downloads-page reports are searchable through selected editorial guides and topic names; the original files and full book text are not published. Full Drive reports are not copied into search. Substack subscriber titles and public summaries are included; full subscriber content opens on Substack. Video transcripts are added when available.