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YouTube·YouTube publication: Jun 17, 2025

Want to actually reverse plaque buildup in your arteries—not just slow it down? 🫀

WellnessInflammation
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Original sourceDan Purser MD on YouTube

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YouTube captions · Unreviewed · Imported 2026-09-24

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0:02

Hey, this is Dr. Dan Perer on plaque regression. How to get plaque to leave your arteries. You don't want plaque there or in your legs. You want it gone from everywhere or for men if they have ED problems in their penis. So, there are five things. They're really seven, but they're five easier things that you could do. I know a lot of you are very

0:17

anti-atin. I'm still going to have to discuss it here. So, I get it. But when I've got a patient with bad coronary artery disease, basically either bypass graph surgery or medicine. By the way, those are the only two things that actually work to prevent heart attacks. By the way, I did not say stin in there

0:33

if you noticed, but there are five things that can cause plaque regression. Let's just start at the top. I'll go with the most natural ones first. First is nascin. I tend to use a controlled release nascin, but nascin 1500 to 2,000 mg a day. And you're going to have some

0:49

flushing even with a controlled release one. Don't be alarmed by the flushing though. It can if you're just taking the cheap non-controlled release stuff off of Amazon or whatever, which you can readily get right now, you may flush like crazy and it's horrifying because you think you're having a drug reaction to the nasin. That's normal. I flushed a

1:05

little last night in the middle of the night cuz I take 2,000 milligrams a day. Also, getting your blood pressure down to below 120 over 80 causes plaque progression. Yes, it does. It's amazing. That's why they picked that number. I know there's a lot of others out there about blood pressure problems are fake and all this kind of stuff. Trust me,

1:21

you want it below 120 over 80. Also, thyroid, you want your FT3, free T3 at around 3.8 to 4.2. Lots of studies showing plaque regression occurs there. People with normal thyroid levels and they're always at the tippy top of the range. They don't have plaque or it goes

1:37

away or causes plaque aggression. There are two statins, simatan that cause really good plaque aggression. I don't know why doctors use the statins they use. Those are the two I use and I featured in my textbook on preventive medicine. Simbic and rubacetin max dose cause has really good

1:52

plaque regression. If you give them with niain you get great plaque regression. I'm going to go six things. I just went over the six one. The other option is a zetto or zedia 10 milligrams. Really easy to use and uh it causes plaque regression too. So nasin a zetto if you

2:08

don't want to take a satin are really good options. By far and away the best option out there is poglitazone. You can get generic poglazone 15 milligrams. It is a diabetic medication. So you got to watch for hypoglycemia. It causes massive plaque regression. Talk to your

2:23

cardiologist or primary care physician about getting on some of these. Some of these you don't need anyone to help you with. You can do it on your own. And good luck with your plaque regression. If not, I'm more than willing to talk. I'm here. This is Dr. Dan Perer.

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Heart health & circulation

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PURSER WELLNESSFree T3 — lab referenceFrom the reading room
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Free T3 — lab reference

Useful in selected hyperthyroid states; not a sensitive stand-alone test for hypothyroidism.

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PQQ (Pyrroloquinoline Quinone)

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