Let’s explore “Cytokines, including IL-6 and TNF-α — lab reference”

IL1B encodes interleukin-1 beta, a cytokine involved in inflammatory responses and fever. Its production and activation are regulated processes, not simply an on/off consequence of having a common SNP.

IL22 encodes a cytokine that acts on tissues such as epithelial barriers. It can support barrier defense and repair, while its effects depend on the tissue and inflammatory setting.

IL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.

IL5 encodes interleukin-5, a cytokine important to eosinophil growth, survival and activation. Eosinophils are involved in selected allergic and other inflammatory conditions.

PURSER WELLNESSWhere To Find Dr. Purser Online (Deplatformed)A conversation with Dr. Purser

Dr. Dan Purser here with an important update from Purser Wellness. Earlier this week we were deplatformed on a major platform right after discussing groundbreaking findings from our homocysteine research — particularly its connections to ASD, ADHD, cytokine issues, and inflammatory conditions like polymyalgia rheumatica (PMR). Despite losing access to our old page (and nearly 200,000 followers), we’re back stronger with a brand new official page! ✅ Follow our new official Facebook page here: https://www.facebook.com/purserwellness We’re keeping things focused and continuing our important work on root-cause wellness, intracellular nutrient deficiencies, genetics, glutathione/SOD balance, and more. ### Where to Stay Connected: - Substack (Daily research articles & in-depth content): https://substack.com/PurserWellness or https://danpursermd.substack.com - YouTube – Live streams and full recordings will continue here (plus TikTok, Instagram, and podcast platforms) Dr. Purser’s message is clear: We will not stop the research. “I’ll quit when I die… and maybe not even then.” If you’ve been following our work on homocysteine, MTHFR, cytokine problems, hormone optimization, and functional medicine protocols, please: - Like and follow the new Facebook page - Subscribe to Substack - Share this video with friends and patients who need this information Thank you for your incredible support during this transition. Your follows and shares help us keep delivering the cutting-edge research no one else is doing. 👉 New Facebook Page: https://www.facebook.com/purserwellness Purser Wellness Root-Cause Medicine • Genetics • Homocysteine Research danpursermd.com #DrDanPurser #PurserWellness #Homocysteine #FunctionalMedicine #RootCauseHealth #CytokineResearch #ASD #ADHD #MTHFR

PURSER WELLNESSPurser Wellness Open House Livestream Recap: Root-Cause Medicine, Breakthroughs in Inflammation & RA conversation with Dr. Purser

https://danpursermd.substack.com/p/purser-wellness-open-house-livestream?utm_source=youtube

PURSER WELLNESSPurser Wellness Open House | Livestream with Dan Purser MD and Team!A conversation with Dr. Purser

Dan Purser MD and the full team will take you on a virtual tour of the clinic, share our root-cause approach to hormones, inflammation, longevity, genetics, and personalized wellness, and answer your questions in real time. You’ll get an inside look at how we help patients reclaim energy, reduce inflammation, and dramatically improve quality of life — plus see the wellness stations, giveaways, and special event offers happening in-person. Whether you’re local or across the country, this is your chance to connect, learn, and discover what true root-cause medicine looks like. And only for the next 24 hours, we have discounted our Testing and Consult Bundles! Jump over to danpursermd.com for a look under the testing tab! We can’t wait to see you (virtually)! 🚀

PURSER WELLNESSUnable to Detox From Inflammation?A conversation with Dr. Purser

Jackson Larkin, one of our Purser Wellness Coaches discusses the need to support your Inflammatory Marker Genetics and what current supplements help achieve this.

PURSER WELLNESSAUTSIM - What is a potential ROOT CAUSE of Autism? Can it be helped?A conversation with Dr. Purser

What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.

PURSER WELLNESSHomocysteine is the Secret AssasinA conversation with Dr. Purser

Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.

PURSER WELLNESSGlutathione and Your Ability To Detox?A conversation with Dr. Purser

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine storms. That’s why VARS Glutathione is such a breakthrough: it’s reduced, functional, and proven to lower harmful cytokines like IL-8 and MCP-1, giving your body the detox power it needs. After 15 years of research and real patient results, it’s the only oral glutathione that actually works where it matters—inside your cells.

PURSER WELLNESSFrom ER Hell to Recovery: A Sarcoidosis Patient’s Remarkable Turnaround with Dr. Dan PurserA conversation with Dr. Purser

Dan Purser MD interviews a patient with a brutal sarcoidosis case involving sky-high SIL2R cytokines, GI sarcoid, heart damage, and years of being dismissed by doctors. After spleen removal, repeated ER visits, and nitroglycerin dependence, he finally found answers. Learn how cytokine testing and the VARS Trio (Glutathione + SOD + Catalase) led to rapid improvement — going from bedridden fear to playing with grandkids in just weeks. This episode highlights the power of root-cause medicine for complex inflammatory conditions and offers hope for those who feel lost in the system. Perfect for listeners dealing with sarcoidosis, chronic inflammation, autoimmune issues, or cytokine-related symptoms. #Sarcoidosis #Cytokines #VARS #PurserWellness #ChronicIllnessRecovery Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd