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Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.

Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.

VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low.

ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficiency.

Good questions deserve a deeper conversation. Purser Wellness Explore is a new space to follow yours - videos, articles, and guided journeys with me. Start with MTHFR, cytokines, homocysteine, gut health… or whatever thread you’re holding

Explore folate, vitamin B9, one-carbon metabolism, anemia, homocysteine, SLC19A1, and differences between folate forms and transport pathways.

Explore rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and double homozygosity.

Explore the reduced folate carrier (RFC1), rs3788200, rs1051266, intracellular folate, homocysteine, and folinic acid and methylfolate.

For many people living with fibromyalgia, movement can feel impossible during a flare. But for some, the right kind of movement—especially low-impact exercise like swimming—can provide a sense of relief, restore confidence, and make it ea

What if 90 days could change the way you think about your health? For some people, making targeted dietary changes can be an important step toward understanding how nutrition affects the way they feel. That's why the 90-Day Strict Low Co

Could an overlooked lab marker be providing valuable insight into your health? Understanding your homocysteine level may help you and your healthcare provider identify opportunities to support cardiovascular health, healthy methylation, an

🔬 What is VARS? Why the VARS Trio (Glutathione + SOD + Catalase) is a game-changer for inflammation, recovery & fibromyalgia. Jackson Larkin sits down with Lois Schweiger to break down Dr. Dan Purser MD’s VARS line — Validated, Absorbable, Reduced, and Stable antioxidants. Learn the science behind VARS Glutathione, VARS SOD (from deep-sea algae near volcanic vents), and the newest VARS Catalase (Nrf2 activator from seaweed). Discover: • How the VARS Triad works together in the mitochondria to fight oxidative stress and cytokines • Why Catalase dramatically improved post-workout recovery (especially leg day!) • Genetics, homocysteine, PEMT, and why many with fibro benefit from this protocol • The importance of CMA (intracellular) testing and when to retest • Real patient results, including severe inflammation cases Perfect for anyone dealing with chronic pain, inflammation, slow recovery, or looking for root-cause support. **June Anniversary Special**: $100 off Genetic + CMA testing — one order will be fully reimbursed! 👉 Learn more & shop VARS supplements: danpursermd.com #VARSGlutathione #Fibromyalgia #Antioxidants #ChronicInflammation #PurserWellness #Catalase #SOD Timestamps: 00:00 Intro & What Does VARS Mean? 01:45 The Science of the VARS Triad 12:00 Who Needs the Trio? 14:00 Catalase & Workout Recovery Stories 20:00 Genetics, Homocysteine & Testing Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd