Let’s explore “folate”

FOLR3 is the gene symbol used for Folate Receptor 3. This page connects its terminology with the topics in the Purser Wellness teaching library.

Encodes the reduced folate carrier, a protein involved in transporting folates into cells.

This report overview covers rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and the report’s discussion of double homozygosity.

You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

PURSER WELLNESSWhat is MTHFR? What can YOU do about it?A conversation with Dr. Purser

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

PURSER WELLNESSWhat Happens If You Have A Gene SNP?A conversation with Dr. Purser

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

PURSER WELLNESSGene Types ExplainedA conversation with Dr. Purser

Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.

PURSER WELLNESSPossible Cause of Crohn's Disease?A conversation with Dr. Purser

Dr. Purser talks about a meta-analysis where correlations are drawn between Crohn's disease, ulcerative colitis, inflammatory bowel diseases, and B12 folate deficiencies. However, it is unclear how each are directly related. PubMed Study: https://pubmed.ncbi.nlm.nih.gov/28406440/ Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

PURSER WELLNESSMTHFR and The 85% SolutionA conversation with Dr. Purser

Do you have problems with depression but most antidepressants made it worse? Are you fatigued all the time despite stimulants and amphetamines doctors readily prescribe? Do regular vitamins give you a stomach aches and nausea? The newest book from best-selling (ten #1 books on Amazon) author Dan Purser MD addresses these issues. Learn how most of the United States population carries the gene for this mysterious disorder, MTHFR. An increasing number of people realize they suffer from symptoms of MTHFR (methylation problems, folate deficiencies, and lack of methylfolate). Learn how it's killing

Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and S

PURSER WELLNESSGe Gene SNPs Cause Vitamin Deficiencies?A conversation with Dr. Purser

Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and SOD decreasing antioxidant defenses against free radicals. These deficiencies drive inflammation, fatigue, and chronic illness, but with the right genetic and intracellular testing, you can target them and supplement with the exact forms your body needs Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialize