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YouTube·YouTube publication: Oct 30, 2025

Ge Gene SNPs Cause Vitamin Deficiencies?

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Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and SOD decreasing antioxidant defenses against free radicals. These deficiencies drive inflammation, fatigue, and chronic illness, but with the right genetic and intracellular testing, you can target them and supplement with the exact forms your body needs

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Original sourceDan Purser MD on YouTube

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Do genetics cause vitamin deficiencies? This is a question we get very often. If the gene snips that you have have the potential to cause deficiencies. Absolutely. Yes. Uh that's one of the main things that we deal with with all of our patients. We specifically look at what gene simps they have so that we can

accurately put them on the right supplements. So Dr. Perser always says, "Good nutrition in equals good hormones out or good wellness out." Um, and so that is definitely controlled by your genes. What deficiencies do you have inside of your cells? And so let's talk

about a couple different ones that may be causing you certain deficiencies. MTHFR is one of the number one gene snips that we see that cause major B vitamin deficiencies. So, MTHFR in general is the inability to

process folate correctly. And so, you have to use different versions of folate to get the benefits of it. And so, MTHFR, if you have one of those gene snips, there's a couple different versions, you will have very key vitamin deficiencies causing all kinds of symptoms. Another one that we see is

PEMT uh which is a gene that's responsible for the production and absorption of phosphotidal choline which is a critical phospholipid used in every cellular membrane throughout your body especially in your gut u especi in your

stomach where those cells have to be regenerated constantly. If you have a PEMT deficiency, you will have very low levels of phosphotylcholine and so you need a supplement and help your body out where it doesn't have what it needs. Another major one that we'll see is sod

or super oxide dismutase SOD 1 2 or three. If you have any one of those gene snips, you're going to have very low levels of either sod 1 2 or three. If you're low in super oxide dismutase, you're going to have a lot of oxidative stress and oxidative damage. Sod SOD is

the frontline defense against the super oxide radical. And this is a free radical, a very dangerous one that's created or that can happen in every single cell in every single mitochondria of your body. And so we have the defense mechanism of superoxide dismutase. If

you have one of the gene snips for it, you'll have a lower efficiency protection against these super oxides. So, do genetics do genetics cause vitamin deficiencies? Absolutely yes. But there's a lot that we can do to help that. Reach out to our office, get our

gene testing, get our our CMA, intracellular testing, and that is the perfect place to start for everything that we we can do to help you. Reach out. Fix.

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Genetic testing, one term at a time

Mentions snps.

Your MTHFR starting point

Mentions mthfr in the captions.

Genetics topic Watch at 0:39 ↗

Gut health, PEMT & choline

Mentions pemt in the captions.

Gut health topic Watch at 1:12 ↗

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