Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and SOD decreasing antioxidant defenses against free radicals. These deficiencies drive inflammation, fatigue, and chronic illness, but with the right genetic and intracellular testing, you can target them and supplement with the exact forms your body needs.