Can the B vitamins you are taking to support energy and methylation eventually make you feel worse?
In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as:
• 5-MTHF or methylfolate
• Methylcobalamin
• Trimethylglycine, also called TMG
• Multiple overlapping methylation formulas
Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.”
These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered.
In this video, we discuss:
• Why methylation is essential
• How methyl-donor supplements support the body
• Why the right vitamin can become the wrong dose
• Ingredients to look for on your supplement labels
• Why some people may need lower doses or non-methylated forms
• How genetics and intracellular nutrient testing can guide a more personalized plan
At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual.
Learn more or schedule with Purser Wellness:
https://danpursermd.com
Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional.
#Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness
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The goal is not just getting a diagnosis.
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Dr. Dan Purser here with an important update from Purser Wellness.
Earlier this week we were deplatformed on a major platform right after discussing groundbreaking findings from our homocysteine research — particularly its connections to ASD, ADHD, cytokine issues, and inflammatory conditions like polymyalgia rheumatica (PMR).
Despite losing access to our old page (and nearly 200,000 followers), we’re back stronger with a brand new official page!
✅ Follow our new official Facebook page here:
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We’re keeping things focused and continuing our important work on root-cause wellness, intracellular nutrient deficiencies, genetics, glutathione/SOD balance, and more.
### Where to Stay Connected:
- Substack (Daily research articles & in-depth content):
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or https://danpursermd.substack.com
- YouTube – Live streams and full recordings will continue here (plus TikTok, Instagram, and podcast platforms)
Dr. Purser’s message is clear: We will not stop the research. “I’ll quit when I die… and maybe not even then.”
If you’ve been following our work on homocysteine, MTHFR, cytokine problems, hormone optimization, and functional medicine protocols, please:
- Like and follow the new Facebook page
- Subscribe to Substack
- Share this video with friends and patients who need this information
Thank you for your incredible support during this transition. Your follows and shares help us keep delivering the cutting-edge research no one else is doing.
👉 New Facebook Page: https://www.facebook.com/purserwellness
Purser Wellness
Root-Cause Medicine • Genetics • Homocysteine Research
danpursermd.com
#DrDanPurser #PurserWellness #Homocysteine #FunctionalMedicine #RootCauseHealth #CytokineResearch #ASD #ADHD #MTHFR
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