NR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions. Also called: Nuclear Receptor Subfamily 3 Group C Me…
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What’s searchable?NTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter. Also called: Neurotrophic Re…
Makes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency. Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine …
PON1 is discussed in relation to how the body handles some compounds and protects certain fats. Also called: Paraoxonase 1 A different part of antioxidant handling PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and…
PTGS2, commonly called COX-2, encodes an enzyme involved in prostaglandin production. Prostaglandins participate in pain, fever and inflammatory signaling. Also called: COX2, Cyclooxygenase 2 COX-2 and inflammatory prostaglandins PTGS2, com…
TCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status. Also called: Transcobalamin II B12 must be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…
TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer. Also called: Tumor Necrosis Fact…
VKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor. Also called: Vitamin K Epoxide Reductase Complex Subunit 1 Recycling vitamin K a…
How the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment. Also called: From a laboratory flag to a useful plan Start with your original CMA report: check its date, values, and the lab’s catego…
Separate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit. Also called: Keep the original result in view Start with your original report: check the date, units, the lab’s range,…
Encodes the reduced folate carrier, a protein involved in transporting folates into cells. Also called: RFC1, reduced folate carrier, folate transport Folate transport is part of the story Dr. Purser’s folate map includes transport as well …
ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…
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