Let’s explore “B vitamins”

Dan and Jackson discuss methylated B vitamins, the term overmethylation, and questions to ask when your response to a supplement changes.

PURSER WELLNESSOVER-METHYLATION - Are Your B Vitamins Hurting You?A conversation with Dr. Purser

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSWhy do I need methylated B Vitamins?From the reading room

Many vitamins and minerals go through the methylation cycle meaning a methyl group is added to a molecule to turn it into its active form. Individuals with MTHFR and other genetic methylation errors are unable to efficiently create the methylated versions of those certain vitamins and minerals. Those with MTHFR specifically cannot make enough 5-MTHF, an activated form of folate, which in turn prohibits the ability to methylate other vitamins. These errors can lead to a number of cellular deficiencies which can cause chronic fatigue, anxiety, depression (BASICALLY MAKE YOU FEEL LIKE A SLUG) and

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model, which explains why homo

PURSER WELLNESSHow To Know If You Have High Homocysteine?A conversation with Dr. Purser

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

PURSER WELLNESSHow to Properly Treat Kids: Root Cause Medicine for Autism, ADHD, and Developmental ChallengesA conversation with Dr. Purser

….com if you want to look me up. Um, I've given a lot of Facebook lives over the years. I've I've had a few that had over a million views. Um, they had over a million people in attendance. This one should be that. It should have two million,…

PURSER WELLNESSDan Purser MD - Live Q&A and Round Up!A conversation with Dr. Purser

Is he on? What do we do? He's on. I can hear you. Be calm. Be happy. You didn't want to use your computer, remember? Well, you had a camera you were going to use like he does. I don't have that stuff here with me. I can ask to do this. I as…

PURSER WELLNESSFill the Holes of Methylation #substack #shortsA conversation with Dr. Purser

And that's what I love about our MTHFR uh the intracellular testing that we do and our MTHFR daily product. We we designed MTHFR daily based off of all of the recent 15 or 20,000 intracellular tests that we got and combined with which ones …

PURSER WELLNESSMTHFR and the Never-Ending Sugar Crash Cycle: Why You’re Tired, Craving Sugar, and Chasing Energy AA conversation with Dr. Purser

…neverending sugar crash cycle. You may have seen a recent Substack post of ours. Make sure to go follow the personal wellness Substack as well as my own Substack if you want to. I do a couple little articles here and there. But one of our l…

PURSER WELLNESSMTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving SweetsA conversation with Dr. Purser

…neverending sugar crash cycle. You may have seen a recent Substack post of ours. Uh make sure to go follow the personal wellness Substack uh as well as my own Substack if you want to. I do a couple little articles here and there. But one of…

PURSER WELLNESSFrom Bedridden to Thriving: Our Real Fibromyalgia JourneyA conversation with Dr. Purser

But it's okay. Okay. Hi guys. We're here with Dan Perer MD today, Purser Wellness. And we have, who do we have here with us today, guys? Uh Lois Schwigger from N Fibro with Natural Options. And Denise Perer with Purser Wellness. I'm Chantel…

PURSER WELLNESSAutism Answered - Root Cause Solved with #1 Reviewed MD in the USAA conversation with Dr. Purser

Boom boom boom. Oh, I'm on. Okay. [laughter] Hey, this is Dr. Dan Perer. Let's dig into this. Um, this is my autis I've really I've really been worrying about this, thinking about this, pondering this for weeks. Um, and so you're going to h…