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Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.

Dr. Purser talks about a meta-analysis where correlations are drawn between Crohn's disease, ulcerative colitis, inflammatory bowel diseases, and B12 folate deficiencies. However, it is unclear how each are directly related. PubMed Study: https://pubmed.ncbi.nlm.nih.gov/28406440/ Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

Do you have problems with depression but most antidepressants made it worse? Are you fatigued all the time despite stimulants and amphetamines doctors readily prescribe? Do regular vitamins give you a stomach aches and nausea? The newest book from best-selling (ten #1 books on Amazon) author Dan Purser MD addresses these issues. Learn how most of the United States population carries the gene for this mysterious disorder, MTHFR. An increasing number of people realize they suffer from symptoms of MTHFR (methylation problems, folate deficiencies, and lack of methylfolate). Learn how it's killing

Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and S

Yes—your genetics can directly cause vitamin deficiencies. Certain SNPs lower your body’s ability to process or make key nutrients, like MTHFR reducing folate use, PEMT lowering phosphatidylcholine production for gut and liver health, and SOD decreasing antioxidant defenses against free radicals. These deficiencies drive inflammation, fatigue, and chronic illness, but with the right genetic and intracellular testing, you can target them and supplement with the exact forms your body needs Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialize

Copper is essential for life—it helps enzymes work, supports SOD1 for antioxidant defense, and even prepares iron to carry oxygen in the blood. But when copper builds up in the bloodstream instead of entering cells, it causes pain, tender points, and migraines. This often ties back to genes like CBS, NAT2, and glutathione-related SNPs that impair copper transport. The solution is supporting ceruloplasmin—the copper-binding protein—with targeted nutrients like B6, zinc, and NAC. That’s why Copper Balance was created: to move copper where it belongs and help symptoms finally improve. Visit PhysicianDesigned.com or Amazon for Copper Balance. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore

If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore iron levels within a few months. Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Many patients with POTS (Postural Orthostatic Tachycardia Syndrome) are told it’s “just bad luck,” but often it’s linked to key nutrient deficiencies. Low levels of B12, folate, copper, and glutathione can impair blood vessel and nervous sy

Doctors have spent decades trying to lower homocysteine with B6, B12, folate, or $12,000/month injections. But it’s not the homocysteine doing the damage—it’s the IL-8 and MCP-1 cytokines it releases. That’s where glutathione (especially VARS or Glutaryl) changes the game. We’ve seen cytokine levels drop to zero—and symptoms vanish. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

🧬 After reviewing over 78,000 tests, Dr. Purser sees the same deficiencies over and over again—especially in fibro patients: Copper & zinc (often imbalanced): Glutathione, B6, B12 & folate, Glutamine, boron, molybdenum, And don’t forget mag