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Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

What if the real threat to your heart isn’t cholesterol at all? For decades, cholesterol has taken the blame. But what if we’ve been focusing on the wrong marker while something far more dangerous goes unchecked? Homocysteine doesn’t get

What if everything you’ve been told about PCOS is missing the real culprit? Homocysteine isn’t just a random lab marker—it may be the hidden thread tying together hormone imbalance, inflammation, and the symptoms so many are struggling to m

This is a clip from https://danpursermd.substack.com/p/high-homocysteine-mthfr-mutations?utm_source=youtube_shorts See the full video: https://www.youtube.com/watch?v=HuQbQ1IqNIM #shorts #substack

Follow Dr. Purser! Are you struggling with unexplained fatigue, muscle pain, or brain fog? High copper levels could be the hidden culprit—and fibromyalgia could be the diagnosis. Learn the key signs to watch for and how to take control of your health. #insulin #genetics #vitamins #Vars #wellness #PEMT #inflammation #glutathione #MicronutrientTesting #FunctionalMedicine #SOD #Homocysteine #ChronicInflammation #MethylationMatters #FunctionalWellness #GeneticTesting #NutrientDeficiency #MTHFR #fibromyalgia #Methylation #DrDanPurser #PurserWellness Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Did you know your body’s natural defense against aging and inflammation quietly declines as you get older? Most people don’t realize that glutathione—the “master antioxidant”—drops with age, genetics, and high homocysteine. The result? More

What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.

Struggling with inflammation, high cytokines, or conditions like psoriasis, kidney disease, or chronic fatigue? The root cause could be elevated interleukins like IL-8 and MCP-1, often triggered by high homocysteine levels. The most powerful natural solution we’ve found?

Struggling with high blood pressure that just won’t budge—even with multiple meds? It might be due to genetic issues causing high homocysteine , which can stiffen your arteries through IL-8 and MCP-1 cytokines.

Top genes to keep an eye out for - homocysteine related genes, PEMT, and VDR. GET THESE ALL IN CHECK! If they are out of whack you’re gonna have a lot of problems, but we can address them. Get genetic testing and and Intracellular nutrient test and we go from there. Reach to my practice to get going. You got this.

Homocysteine is bad for you, but it’s a critical part of the transsulfuration pathway. You don’t make glutathione wothout it, but when your levels of homocysteine get too high, it becomes majorly problematic for you.

Most chronic inflammation, gut issues, and detox problems aren’t aging or bad luck — they’re methylation disorders your doctor probably ignores. MTHFR and homocysteine matter more than mainstream medicine admits, and the research is about t