Most chronic inflammation, gut issues, and detox problems aren’t aging or bad luck — they’re methylation disorders your doctor probably ignores. MTHFR and homocysteine matter more than mainstream medicine admits, and the research is about to change everything.
Search covers the published post or caption. Load the original post above to view its media. Image text and spoken audio are not transcribed here. Hashtags are omitted for readability.
A term in this discussion
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
A term in this discussion
Learn the vocabulary before trying to interpret a pathway.
More on Understanding inflammation
Come chat with Dan Purser MD and Jackson Larkin about all things Purser Wellness - Catch up on new testing, products, books, and MORE!
More on Understanding inflammation
Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.
