Explore the reduced folate carrier (RFC1), rs3788200, rs1051266, intracellular folate, homocysteine, and folinic acid and methylfolate.
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What’s searchable?Encodes the reduced folate carrier, a protein involved in transporting folates into cells.
…cid are different compounds measured for different reasons. Folate transport and one-carbon metabolism are relevant to homocysteine handling. Follow the pathway Dr. Purser discusses SLC19A1, folate availability, methylation, and metabolic …
Explore folate, vitamin B9, one-carbon metabolism, anemia, homocysteine, SLC19A1, and differences between folate forms and transport pathways.
FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step. Also called: Folate Hydrolase 1 Folate handling begins before remethylation Dr. Purser’s genetic chapters include FOLH1 in folate handling…
Follow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine. Also called: Follow the branches around homocysteine Homocysteine sits at a junction in the pathway. Dr. Purser’s teaching follows ho…
…ing conclusions about homocysteine. How the pieces connect Folate, B12, and sulfur pathways involve many genes. The exact variant and its classification tell you more than a gene name or a colored app result. Read the variant, not just th…
Supports DNA synthesis and one-carbon metabolism, including the pathway that processes homocysteine.
<4.0 suggests deficiency. Recent intake or supplementation may raise serum values.
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.
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