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Gene referenceSep 23, 2026
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…mmatory signaling. Putting the pieces together Dr. Purser’s notes connect COX-2 genetics with responses to anti-inflammatory medicines. A marker does not prove that a COX-2 inhibitor will fail. Medication choice should consider the actual r…

Gene referenceSep 23, 2026
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…ion or choose a supplement dose for you. Variant IDs in the teaching reference: rs1979277 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS G…

Gene referenceSep 23, 2026
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…ion or choose a supplement dose for you. Variant IDs in the teaching reference: rs202445, rs2070424, rs2234694 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and t…

Gene referenceSep 23, 2026
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…ion or choose a supplement dose for you. Variant IDs in the teaching reference: rs10370, rs2855116, rs4880, rs5746105, rs5746136 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss…

Gene referenceSep 23, 2026
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…ion or choose a supplement dose for you. Variant IDs in the teaching reference: rs1799895, rs2284659, rs2855262, rs8192287 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR…

Gene referenceSep 23, 2026
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…be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it concerns the transport of B12. The teaching distinction is between eating or supplementing a vitamin, transporting it, and using it in a…

Gene referenceSep 23, 2026
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…Purser emphasizes TNF in his inflammatory and tissue-damage teaching and places VARS Glutathione within his redox-support framework. That approach does not replace evaluation of infection, autoimmune disease or another cause of inflammation…

Gene referenceSep 23, 2026
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…itamin K receptor. Putting the pieces together Dr. Purser’s notes flag this pathway because it matters to clotting and medication response. Certain variants can alter warfarin dose requirements, including increased sensitivity; they do not …

Learning essentialsSep 23, 2026
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…rocesses. Putting the pieces together The VARS Triad is his teaching framework for discussing glutathione, SOD and catalase together. Current nutrient/redox findings, genetics, symptoms and tolerance determine the clinical conversation. A p…

Gene referenceSep 23, 2026
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…well as conversion. SLC19A1 is a folate transporter, so its teaching role differs from MTHFR: getting folate into cells is a separate step from changing it into another form. Putting the pieces together SLC19A1 helps transport folate into c…

Gene referenceSep 23, 2026
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…trient deficiency. Putting the pieces together Dr. Purser’s notes bring ALPL into the B6 and bone-health conversation. A common marker such as rs4654748 is not itself a diagnosis of hypophosphatasia. Bone pain, poorly healing fractures, ear…

Gene referenceSep 23, 2026
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…-aging and diabetic-neuropathy contexts. Those research and teaching links should not be read as a direct measure of neurogenesis or proof that a SNP causes cognitive slowing. Memory and neuropathy symptoms need their own assessment. A ques…

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