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Books & reading guidesFrom the archive
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…gnose the effect of a gene finding. Pathway names describe different jobs Remethylation and transsulfuration are connected, but they are not the same process. Dr. Purser discusses MTHFR alongside CBS, MTR, MTRR and SHMT1 because these gene…

Books & reading guidesFrom the archive
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…used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Topics: homocysteine, pain, cytokines, chronic pain, neuroinflammation, oxidative stress

Books & reading guidesFrom the archive
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…t breakdown; CRP relates to inflammation; homocysteine is a different molecule. Ask what each test was ordered to investigate. Different markers answer different questions Dr. Purser puts several measurements next to one another, but a sha…

Books & reading guidesFrom the archive
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…used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Topics: homocysteine, glutathione, monocytes, IL-8, MCP-1, reactive oxygen species, cytokines

Books & reading guidesFrom the archive
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…gs genetics and toxicants into one model, but they describe different things. Susceptibility is a possible tendency to respond differently; exposure is contact with a substance. A gene result does not establish that an exposure occurred. Dr…

Books & reading guidesFrom the archive
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…anies greater cardiovascular risk. A treatment study asks a different question: does an intervention reduce events? Differences in study design, underlying illness and the chosen outcome matter. Read a reported change in homocysteine beside…

Books & reading guidesFrom the archive
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…for an inherited disorder and an ordinary balanced diet are different situations. Read this discussion’s criticism of restriction within the population it addresses, rather than using it to overturn a medically prescribed nutrition plan. K…

Books & reading guidesFrom the archive
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…used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Topics: Skyrizi, risankizumab, IL-23, homocysteine, psoriasis, Crohn’s disease, ulcerative colitis

Books & reading guidesFrom the archive
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…used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency. Topics: IL-8, CXCL8, occult infection, persistent inflammation, homocysteine, cytokines

Books & reading guidesFrom the archive
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…y, testicular, thyroid, and nutrition questions can lead to different tests. Finding a low number is only the beginning. The location of a problem changes the question Dr. Purser separates pituitary, testicular, thyroid and nutritional ide…

Books & reading guidesFrom the archive
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…wel disease can affect nutrition and absorption. Treating a deficiency and controlling bowel inflammation are related but different goals. Separate the bowel disease from nutritional consequences The study guide connects inflammatory bowel…

Health BlogOct 2, 2026
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Most doctors run standard serum blood tests, see a "normal" nutrient level, and send you home. But measuring floating nutrients in your liquid serum is like looking at the paint on a house to see if the plumbing works inside. After reviewing over 40,000 advanced intracellular vitamin lab panels, the truth is clear: intracellular glutathione vs serum levels tell two entirely different stories. Your serum can look completely fine while your cells are completely depleted of the master antioxidant needed to protect your life. The Cytokine Threat When methylation breaks down and homocysteine elevat

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