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… level is not just about what you eat. Nutrition matters. Folate matters. Vitamin B12 matters. Vitamin B6 matters. Lifestyle matters. Genetics may matter too. So why are we waiting until disease appears before asking what our biology…

…r picture. Variants such as C677T and A1298C can influence folate metabolism and methylation. Stop blaming yourself. Start understanding the biology. Support your nutrition. Support methylation when appropriate. Prioritize protein,…

…THFR gene variants (common in ~85% of people). These impair folate processing → elevated homocysteine → massive inflammation and cytokine storms (IL-6, TNF-α, IL-17, etc.). High homocysteine (>10-12 µmol/L; ideal <7-8) acts like a "cytokin…

…gle-nucleotide changes reduce the enzyme methylenetetrahydrofolate reductase activity by 30–70%, impairing the conversion of folate into its active form (5-methyltetrahydrofolate). The downstream result? Impaired methylation, elevated plasm…

…ome don’t matter, but others can throw off key systems like folate metabolism (MTHFR), antioxidant defense (SOD), and glutathione production. While you can’t change your genes, you can support them. At Purser Wellness, we combine genetic an…

…phatidylcholine supplements ✅ Support methylation with B12, folate, & B6 ✅ Improve gut health with high-quality probiotics (like Natren Healthy Trinity) Liposomal Glutathione & Phosphatidylcholine: A Powerful Duo PEMT mutations are often l…

…ey nutrients like iron, vitamin B6, CoQ10, vitamin B12, and folate are instrumental in managing this condition, emphasizing the importance of a well-rounded nutrient intake. Migraines: Similar to fibromyalgia, migraines may benefit from bo…

…e intracellular level. That's how I figured out this was a transport problem -- i.e. the ceruloplasmin is dysfunctional. This dysfunctionality is due in part to OTHER vitamin deficiencies. In turn all these deficiencies explain their CFS…

… follow it. The deficiencies cause a dysfunction in copper transport and so these patients develop copper overload or toxicity. SEE YOU TUESDAY NIGHT -- START YOUR JOURNEY TO WELLNESS THEN.

…roduction: MTHFR is a gene related to the enzyme processing folate. Errors here can lead to energy production issues. Products like MTHFR Renew, MTHFR Endure, and VARS Glutathione are designed to counteract these issues, ensuring optimal en…

… more energy. CoQ10 works specifically along the electron transport chain, the energy production pathway within mitochondria, as the last cofactor in this production line. ATP cannot be created without ubiquinone, the version of CoQ10 tha…

…els look great. 2. The defective enzyme doesn’t break down folate vitamins properly (of which folic acid is the precursor to), which can cause high homocysteine levels (hyperhomocysteinemia), which causes vascular inflammation which in tur…