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PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

How the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.

How Dr. Purser combines inherited tendencies, current nutrient findings and conventional laboratory results without treating them as the same test.

Explore skin-barrier symptoms, acantholysis, cytokine networks, and redox management.

Explore rs2857261, rs1057972, natural killer cells, CD8+ T cells, and questions about high-expression variants.

Explore migraine, neurovascular inflammation, trigeminal signaling, CGRP, and related research.

Explore monoamine oxidase, the MAOA and MAOB genes, rs1137070, rs2072743, rs66323, rs1799836, rs2283729, neurotransmitter metabolism, dietary amines, and treatment research.

Explore multiple sclerosis (MS), central nervous system inflammation, myelin, symptoms, and related immune signals.

Explore tumor necrosis factor-alpha, TNFR1, TNFR2, rs1800629, inflammatory signaling, and treatment comparisons in Purser Wellness teaching.

Dan and Jackson discuss serum testing, intracellular nutrient results, REDOX, and the questions each kind of test addresses.

Dan and Jackson discuss the Algevity ingredient, Nrf2, antioxidant research, and VARS Catalase, including an update on the study’s publication status.