THE PURSER WELLNESS LIBRARY
27 discoveries for your curiosity
What’s searchable?Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.
A subscriber post from Purser Wellness on Substack, covering genetics and methylation.
By Dan Purser MD Pathway-level clinical interpretation focused on inflammatory interaction, likely signs, and likely complications
A subscriber post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.
MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd
Read matching passageGenetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.
Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.
…e, but um he had interesting findings. He had a um a double homozygous MTHFD1 which shouldn't be something you think would cause cardiovascular disease. Oh, but I'm wrong. It definitely causes bad plaque buildup. Uh significant even. I don'…
Read matching passage…e, but um he had interesting findings. He had a um a double homozygous MTHFD1 which shouldn't be something you'd think would cause cardiovascular disease. Oh, but I'm wrong. It definitely causes bad plaque buildup. Uh, significant even. I d…
Read matching passage…ng doesn't matter if you have C677 or A129C and that you're homozygous meaning you have a match pair uh they're they're wrong they're just flat tomorrow because MTHFR C677 and uh A129HC U husband and wife with a bad bad MTHFRs are major cau…
Read matching passage…ng doesn't matter if you have C677 or A129C and that you're homozygous meaning you have a match pair uh they're they're wrong they're just flat wrong because it's a m MTHR C677 and uh A129HC uh husband and wife with a bad bad MTHFRS are maj…
Read matching passage… let us know which one do you have. Are you hetererozygous, homozygous? I'm always super curious to know about that. So, [music] if you have one of these MTHFR snips, that really has to do with folate production, folate manufacturing, folat…
Read matching passageBest match puts all-term matches before partial matches and related reading. Matching long titles across sources are grouped when access is the same. Search covers published titles, descriptions, available article text, report overviews, and the full text of the nutrient, gene and learning-essential reference pages. Books, uploaded chapters and downloads-page reports are searchable through selected editorial guides and topic names; the original files and full book text are not published. Full Drive reports are not copied into search. Substack subscriber titles and public summaries are included; full subscriber content opens on Substack. Video transcripts are added when available.
