If you’re homozygous for the MTRR gene, especially double homozygous, there’s a good chance your body can’t make enough SAMe—a compound critical for mood, energy, and methylation. 🧬 For many with this mutation, taking SAMe can feel like flipping on the lights—boosting energy, lifting mood, and restoring clarity. Dr. Purser recommends Nature’s Trove 200mg SAMe—clean, effective, and lower dose to start. Just one capsule a day can be life-changing—but always watch how you feel and increase slowly. Want help understanding your MTRR status? Email or call our office today.