By Dan Purser MD Pathway-level clinical interpretation focused on inflammatory interaction, likely signs, and likely complications
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Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.
Dr. Purser’s subscriber report on IL-10 dysregulation, immune signaling, and his discussion of the VARS Antioxidant Triad.
Dr. Purser’s subscriber report on IL-17, homozygosity, and the skin, joint, and digestive topics raised in the public introduction.
— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation. This is not fringe theory. It is the clinical reality I have
