IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
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What’s searchable?Explore interleukin-18, caspase-1, the NLRP3 inflammasome, interferon-gamma, and related immune pathways.
Explore interleukin-18 receptor 1, IL-18, IFN-gamma, NF-kappa B, NLRP3, and related inflammation and treatment research.
IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.
IL18RAP encodes an accessory protein in the IL-18 receptor complex. The receptor needs coordinated components to translate an extracellular signal into a cellular response.
Explore interleukin-18 receptor accessory protein, IL18R1, MyD88, and mucosal and systemic inflammation.
Explore the NLRP3 sensor, inflammasome priming and activation, IL-1 beta, IL-18, and pyroptosis.
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