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TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

TNFSF10 encodes TRAIL, a signaling protein involved in regulated cell death through particular receptors. It is a different member of the TNF-related signaling family from TNF itself.

Everyone is talking about collagen, protein, and vitamins. Almost no one is talking about one of your body's most important antioxidant defenses. Superoxide dismutase (SOD) is a naturally occurring enzyme that helps your body neutralize o

Refers to part of the HLA immune-recognition region, rather than one gene. HLA typing requires more detail than a broad region label.

Explore D-amino acid oxidase activator (DAOA / G72), rs2391191, D-serine, NMDA receptors, glutamate signaling, and research questions about brain and mood.

Explore migraine, neurovascular inflammation, trigeminal signaling, CGRP, and related research.

Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.

Three products. Three antioxidant systems. One powerful approach to cellular wellness. Meet the VARS Triad. VARS Glutathione. VARS SOD. VARS Catalase. Each was designed to support an important part of your body's natural antioxidant

Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.

What if the antioxidant conversation is bigger than just one supplement? Glutathione. SOD. Catalase. Three powerful parts of the body's antioxidant defense network. Three different roles. One bigger conversation about cellular wellnes

That afternoon sugar craving may be telling you more than you think. Here’s how methylation, glucose, cellular energy and your genetics may fit into the bigger picture. https://danpursermd.substack.com/p/mthfr-and-the-never-ending-sugar?utm_source=youtube

Fibromyalgia is complex. There is no single cause and no single solution. But research has explored the relationship between fibromyalgia, oxidative stress, and the body's antioxidant defense systems. That is where SOD becomes an inter