CETP
Some search terms matchedCETP transfers cholesteryl esters between lipoprotein particles. This helps explain why the balance of HDL and other lipid particles is more complex than a single cholesterol number.
Also called:
Moving cholesterol between lipoproteins
CET…
CXCL13
Some search terms matchedCXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings.
Also called:
Guiding B cells to organized immune sit…
CXCL8
Some search terms matchedCXCL8 is the gene for IL-8, a chemokine involved in recruiting and activating neutrophils. IL-8 is the protein nickname; CXCL8 is the gene name a DNA report may use.
Also called:
IL-8: bringing neutrophils to the response
CXCL8 is the gene…
CXCR5
Some search terms matchedCXCR5 encodes the receptor for CXCL13. This receptor helps guide B cells and certain T cells toward locations where organized immune responses develop.
Also called:
Following the CXCL13 signal
CXCR5 encodes the receptor for CXCL13. This re…
DDAH1
Some search terms matchedDDAH1 encodes an enzyme that breaks down asymmetric dimethylarginine, or ADMA. ADMA inhibits nitric oxide synthase; DDAH1 is part of its clearance system, not the inhibitor itself.
Also called:
Clearing ADMA helps preserve nitric oxide sig…
F5
Some search terms matchedF5 encodes coagulation factor V. The well-characterized Factor V Leiden variant, rs6025, can make factor V less responsive to an anticoagulant control mechanism, increasing susceptibility to venous clots. It does not mean the body cannot ma…
F9
Some search terms matchedF9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.
Also called:
Factor IX and the bleeding sid…
HMGB1
Some search terms matchedHMGB1 normally has functions inside the cell nucleus. When released outside cells in particular settings, it can act as a damage-associated molecular pattern, or DAMP, participating in inflammatory signaling.
Also called:
A cellular protei…
IFNG
Some search terms matchedIFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses.
Also called:
Interferon gamma and macrophage activati…
IL10
Some search terms matchedIL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one.
Also called:
The immune system al…
IL12B
Some search terms matchedIL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine.
Also called:
A shared component of two cytokines
IL12B encodes the p40 subuni…
IL13
Some search terms matchedIL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal.
Also called:
Allergic signaling and tissue responses
…
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