Homocysteine: The Overlooked Factor in Chronic Disease
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THE PURSER WELLNESS LIBRARY
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What’s searchable?A post from Purser Wellness on Substack, covering inflammation and antioxidants.
Inflammation, Brain Fog, Gut Issues and More
Spring time is when LIFE flourishes, but how are you feeling? Now is the time to make the MOST out of life by getting to the ROOT of your issues. Are you fatigued, anxious, or dealing with inflammation? Let's fix it - and no band aid fix. Let's look at your genes and your deficiences and FIX IT!
Read matching passageThe Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step
The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step https://danpursermd.substack.com/p/can-glutathione-reverse-kidney-disease?utm_source=youtube
A post from Purser Wellness on Substack, covering inflammation and antioxidants, mind, mood, and sleep.
Dr. Purser explains symptoms of Metallothionein dysfunctions and how metal toxicity can cause fibromyalgia. Learn how high serum copper levels cause painful inflammation in muscles, nerves, and joints. Explore the genetic components associated with fibromyalgia. Discover key nutritional supplements that help reduce symptoms of fibromyalgia. Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!
High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even infertility. Genetics play a big role—there are 17 SNPs that can lock homocysteine in place—but vitamin deficiencies can make it worse. The real breakthrough isn’t lowering homocysteine itself but calming the cytokines it triggers, like IL-8 and MCP-1. That’s why VARS Glutathione, the only patented oral form proven to work, is so powerful—it lowers those cy
High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the
Most glutathione supplements fail because they break down before your body can use them. VARS Glutathione is different—it’s patented, validated, and proven to raise real intracellular glutathione levels. That means it actually works to calm inflammation, lower cytokines, and protect your cells where it matters most.
Superoxide dismutase (SOD)—your body’s first line of defense against DNA-damaging free radicals. SOD neutralizes superoxide radicals at the source of cellular energy production. But as we age—or if we have genetic SNPs—our ability to make SOD drops. That’s why we created VARS SOD, with over 10,000 IU per dose (most products have less than 240 IU). It’s a game changer for anti-aging, DNA protection, and reducing inflammation at the root.
High homocysteine? It’s not the number—it’s the cytokines it triggers (like IL-8) that cause strokes, kidney failure & inflammation. We found 17 gene SNPs + 12 vitamin deficiencies that drive it—and VARS Glutathione helps shut it down.
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