TCN2
Some search terms matchedTCN2 helps carry vitamin B12 in the body. A gene result alone cannot tell you your B12 status.
Also called: Transcobalamin II
B12 must be carried as well as consumed
TCN2 appears in Dr. Purser’s homocysteine and methylation map because it c…
VKORC1
Some search terms matchedVKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
Understanding a nutrient deficiency
Some search terms matchedHow the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.
Also called:
From a laboratory flag to a useful plan
Start with your original CMA report: check its date, values, and the lab’s catego…
How to read a laboratory report
Some search terms matchedSeparate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit.
Also called:
Keep the original result in view
Start with your original report: check the date, units, the lab’s range,…
SLC19A1
Some search terms matchedEncodes the reduced folate carrier, a protein involved in transporting folates into cells.
Also called: RFC1, reduced folate carrier, folate transport
Folate transport is part of the story
Dr. Purser’s folate map includes transport as well …
ALPL
Some search terms matchedALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…
CCL3
Some search terms matchedCCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct.
Also called:
MIP-1 alpha and the chemokine cluster
CCL3 encodes MI…
CD40LG
Some search terms matchedCD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted.
Also called:
The ligand that helps acti…
F9
Some search terms matchedF9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.
Also called:
Factor IX and the bleeding sid…
IL16
Some search terms matchedIL16 encodes interleukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.
Also called:
A cytokine involved in immun…
IL18
Some search terms matchedIL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Also called:
An inflammatory signal that connects to int…
IL4
Some search terms matchedIL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Also calle…
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