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Explore transsulfuration, methylation, glutathione, genetic variants, cytokines, and possible connections.

What if the biggest breakthroughs in autism support aren’t coming from symptom management alone? In our latest article, we dive deep into what we’ve seen consistently in practice: how genetic variants (especially MTHFR and related SNPs) ca

Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

CMA testing shows what nutrients are inside your cells, not just floating in your blood, giving a true picture of deficiencies. When combined with Redox, it also tracks inflammation markers and oxidative stress—giving a full view of your he

Glutathione is called the “master antioxidant” because it protects every cell in your body from oxidative damage, supports detox, and reduces inflammation. People with high homocysteine or MTHFR gene variants often can’t recycle glutathione

CMA testing shows what nutrients are inside your cells, not just floating in your blood, giving a true picture of deficiencies. When combined with Redox, it also tracks inflammation markers and oxidative stress—giving a full view of your health and guiding precise supplementation. Reach out to my practice or visit my site to get going on you CMA with Redox! 801-796-7667 and Info@DanPurserMD.com Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

CMA testing shows what nutrients are inside your cells, not just floating in your blood, giving a true picture of deficiencies. When combined with Redox, it also tracks inflammation markers and oxidative stress—giving a full view of your health and guiding precise supplementation . Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Feeling exhausted and super sensitive to supplements? 😩 You might think it’s adrenal fatigue, but in many cases, it’s actually due to vitamin deficiencies—especially in those with MTHFR or FOLR2 gene mutations. These genetic variants can im

Ever heard of glutathione? It’s called the “master antioxidant” for a reason—it supports detox, reduces inflammation, and protects every cell in your body from oxidative damage. 🧬 If you have high homocysteine or MTHFR gene variants, chance

Fatigue, Anxiety, Depression, these are the big three that lead to the Dark Side. MTHFR is a HUGE problem for people that have its variants. You need to plug the holes of a crumbling well, but without the right tools it’s nearly impossibl

Your fatigue is coming from deep in your cells, malnourishment that causes a lack of energy production at a cellular level. The effeciency of Carbohdrate to ATP production is severely lacking if you have MTHFR Variants. Depending on how m