Let’s explore “Genetic variants / SNP findings — lab reference”

…ern. The receptor TNFRSF10A provides the next connection. A genetic marker does not establish that excessive apoptosis is occurring or select an intervention to block it. A question to bring to your visit What measured or clinical evidence …

PURSER WELLNESSThe Master MTHFR Protocol Dr. Purser DesignedFrom the reading room

….) More importantly, mainstream medicine misses the danger: Genetic Risks: Homozygous MTHFR C677T or Homozygous MTHFR A1298C (along with 20 other homozygous methylation SNPs) can be lethal if left unmanaged. Downstream Effects: Unmanaged va…

…rves to be understood alongside kidney function, nutrition, genetics, and other laboratory findings. Your lab results are more than numbers on a page. They are clues that can help you ask better questions about your health. Learn why kid…

…mocysteine expert), the missing link for many is MTHFR gene variants (common in ~85% of people). These impair folate processing → elevated homocysteine → massive inflammation and cytokine storms (IL-6, TNF-α, IL-17, etc.). High homocystein…

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room

…irm the link: MTHFR C677T and A1298C polymorphisms increase genetic susceptibility to rheumatoid arthritis (especially in Asian populations) and systemic lupus erythematosus. In multiple sclerosis, the MTHFR 677TT genotype correlates with h…

… kidney or blood pressure issues. Homocysteine isn’t just a lab number — it’s a toxic byproduct that drives inflammation through cytokines like MCP-1 and IL-8, damaging blood vessels and disrupting hormones. Dr. Purser’s research found up t…

…, leading to inefficient methylation. There are two primary variants of the mutation, C677T and A1298C. People can have one or two copies of each mutation (from either or both parents), affecting the function of the MTHFR enzyme to varying …

PURSER WELLNESSA Natural Approach to Lowering High Blood PressureFrom the reading room

… due to factors such as a lack of exercise, poor diet, or a genetic predisposition to high blood pressure. A 2020 study showed that variations in the CYP24A1 gene can have a strong impact on a person’s risk of developing chronic high blood …

PURSER WELLNESSGMO vs non-GMOFrom the reading room

… products. But what does GMO actually mean? GMO stands for “genetically modified organism ” which can also be said legally as a “living modified organism” or LMO. Usually this is not a problem, however, when it comes to digestion it can be …

…sessment This chapter asks whether an apparently reassuring laboratory number can hide a nutritional problem. That is a useful question, but the proposed answer must be tested rather than assumed. Protein intake, absorption, medicines, othe…

… reading to the cytokine library, then compare experimental findings with clinical studies. Immune cells send recruitment signals The chapter’s model links a metabolic exposure with a response from immune cells. It focuses on monocytes and…

…nssulfuration Pathway Disruption, and Toxicant Exposures in Genetic Hyperhomocysteinemia Homocysteine and environmental exposures The idea to explore This chapter places environmental exposures alongside genetics, sulfur metabolism and in…