PTGS2
Some search terms matchedPTGS2, commonly called COX-2, encodes an enzyme involved in prostaglandin production. Prostaglandins participate in pain, fever and inflammatory signaling.
Also called: COX2, Cyclooxygenase 2
COX-2 and inflammatory prostaglandins
PTGS2, com…
SERPINE1
Some search terms matchedSERPINE1 encodes plasminogen activator inhibitor-1, or PAI-1, which helps regulate fibrinolysis: the process that breaks down clots. The source label PAI4G refers to this pathway rather than a separate gene.
Also called: PAI-1, PAI4G, Plasm…
SHMT1
Some search terms matched…aces SHMT1 in the folate-interconversion network.
Also called: Serine Hydroxymethyltransferase 1
Where amino acids meet folate
The course places SHMT1 in the folate-interconversion network. Its enzyme connects serine and glycine metabolism …
SOD1
Some search terms matchedDr.
Also called: Superoxide Dismutase 1
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD1 works primarily inside cells and uses copper and zinc. SOD converts superoxide into hydrogen per…
SOD2
Some search terms matchedDr.
Also called: Superoxide Dismutase 2
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD2 works in mitochondria and uses manganese. SOD converts superoxide into hydrogen peroxide, which …
SOD3
Some search terms matchedDr.
Also called: Superoxide Dismutase 3
Superoxide defense in its own setting
Dr. Purser teaches SOD as one member of an antioxidant team. SOD3 works outside cells and uses copper and zinc. SOD converts superoxide into hydrogen peroxide, wh…
TCN2
Some search terms matchedTCN2 appears in Dr.
Also called: Transcobalamin II
B12 must be carried as well as consumed
TCN2 appears in Dr. Purser’s homocysteine and methylation map because it concerns the transport of B12. The teaching distinction is between eating or…
TNF
Some search terms matchedTNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.
Also called: Tumor Necrosis Fact…
VKORC1
Some search terms matchedVKORC1 encodes vitamin K epoxide reductase, part of the vitamin K recycling system used in activating clotting proteins. It is not simply a vitamin K receptor.
Also called: Vitamin K Epoxide Reductase Complex Subunit 1
Recycling vitamin K a…
How to read a laboratory report
Some search terms matchedSeparate the gene, variant, measured value and clinical interpretation—and learn which questions to bring to your visit.
Also called:
Keep the original result in view
The uploaded SOPs begin with source verification: the right report, date…
SLC19A1
Some search terms matchedEncodes the reduced folate carrier, a protein involved in transporting folates into cells.
Also called: RFC1, reduced folate carrier, folate transport
Folate transport is part of the story
Dr. Purser’s folate map includes transport as well …
ALPL
Some search terms matchedALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme important to bone and tooth mineralization and vitamin B6 metabolism. Persistently low alkaline phosphatase can deserve a different evaluation from a general nutrient deficienc…
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