…ent, IL18RAP, to support IL-18 signaling.
Also called:
The binding side of the IL-18 receptor
IL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.
How Dr. Purser c…
The Purser genetics reference places CHDH in choline metabolism, while the combined SOP asks clinicians to consider CHDH alongside PEMT and FADS findings.
Can the B vitamins you are taking to support energy and methylation eventually make you feel worse?
In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as:
• 5-MTHF or methylfolate
• Methylcobalamin
• Trimethylglycine, also called TMG
• Multiple overlapping methylation formulas
Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.”
These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered.
In this video, we discuss:
• Why methylation is essential
• How methyl-donor supplements support the body
• Why the right vitamin can become the wrong dose
• Ingredients to look for on your supplement labels
• Why some people may need lower doses or non-methylated forms
• How genetics and intracellular nutrient testing can guide a more personalized plan
At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual.
Learn more or schedule with Purser Wellness:
https://danpursermd.com
Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional.
#Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness
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What if the key to feeling better isn't another health trend—but understanding the nutrients your body depends on every day?
Vitamin C. B vitamins. Iron.
These essential nutrients influence everything from energy production and immune fun
What if the answers you've been searching for aren't found in another prescription—but inside your own cells?
Most lab tests tell you what's circulating in your blood. But what if your cells are telling a different story?
A Cellular Micro
What if everything you’ve been told about PCOS is missing the real culprit?
Homocysteine isn’t just a random lab marker—it may be the hidden thread tying together hormone imbalance, inflammation, and the symptoms so many are struggling to m
What’s the symptom I see that tells me someone needs intracellular vitamin testing? Fatigue—plain and simple. If you’re constantly exhausted, even after doctors have checked your thyroid, iron, and everything else, it could be hidden vitam
Dr. Purser dives into the root causes of low testosterone in men. As always, "Good nutrition in, means good hormones out." Could low testosterone levels be linked to severe vitamin deficiencies caused by genetic errors such as MTHFR? Dr. Purser has found this to be the case for many of his patients. Find out how you can start feeling great today! Testing discussed: SpectraCell Intracellular Micronutrient Panel, Pro7 Genetic Testing, and Direct Labs Free and Total Testosterone Levels. See all testing options at https://DanPurserMD.com/genetics-testing. Contact us at (801) 796-7667 or info@danpu
Thyroid health remains essential during menopause. Optimal labs should show FT3 around 4.0 and FT4 near 1.5, and testing through Direct Labs makes it easy to track. Supporting with supplements like Thyromin can help, but only if guided by accurate lab results.
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
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