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Explore a research question about IL-23 medicines and homocysteine-related inflammation.

See why symptoms and repeat testing both matter when discussing testosterone in men.

Follow the questions linking symptoms, genetics, homocysteine, and immune signals.

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

This week Dr. Purser shares his findings and treatment protocols for Interstitial Cystitis. He classifies this disease as the worst version of fibromyalgia, but covers best ways to treat it. Try a low copper diet, understand your underlying methylation genetics, and use beneficial supplements. Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

What are the basica of MTHFR, how did you get it, what can you do about it? We Dive Deep into the intricacies of MTHFR and methylation issues. Why are you tired all the time? Why are you so low energy? Because you aren’t processing yo

What are the basics of MTHFR, how did you get it, what can you do about it? We Dive Deep into the intricacies of MTHFR and methylation issues. Why are you tired all the time? Why are you so low energy? Because you aren’t processing your cri

Fibromyalgia - let’s break this down into 4 simple steps to Naturally Resolve your symptoms. 1. Low Copper Diet - cut the supplements and foods high in copper for 3 months then slowly start introducing things back in 2. Glutathione - you

Fibromyalgia - let’s break this down into 4 simple steps to Naturally Resolve your symptoms. First, visit End Fibromyalgia with Natural Options here on Facebook for all the guidance. 1. Low Copper Diet - cut the supplements and foods hi

Fibromyalgia Resolution - let’s break this down into 4 simple steps to Naturally mitigate your symptoms. 1. Low Copper Diet - cut the supplements and foods high in copper for 3 months then slowly start introducing things back in 2. Gluta

Intracellular testing, or the CMA Cellular Micronutrient Assay, measures over 100 vitamins, minerals, amino acids, and antioxidants inside your cells—not just in your blood. Unlike serum tests, which show short-term levels, intracellular testing reveals what your cells have been missing over the last 100 days. Low levels can mean weak enzymes, non-functioning proteins, and accelerated aging. By identifying deficiencies and matching them with the correct nutrient forms for your genetics, you can target fatigue, anxiety, depression, and other chronic issues at the root. Get your CMA by calling o

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine storms. That’s why VARS Glutathione is such a breakthrough: it’s reduced, functional, and proven to lower harmful cytokines like IL-8 and MCP-1, giving your body the detox power it needs. After 15 years of research and real patient results, it’s the only oral glutathione that actually works where it matters—inside your cells.